UBE2W and BFAR

Number of citations of the paper that reports this interaction (PubMedID 19549727)
74

Data Source:
BioGRID (two hybrid)

		UBE2W	BFAR
Description		ubiquitin conjugating enzyme E2 W	bifunctional apoptosis regulator
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Endoplasmic Reticulum Integral Component Of Plasma Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity Caspase Binding
	Biological Process	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Response To Misfolded Protein	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of IRE1-mediated Unfolded Protein Response
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cervical high-risk human papilloma virus infection ( 33225922) Malaria ( 31844061) Manganese levels ( 26025379) Urate levels in obese individuals ( 25811787)
Interacting Genes		80 interacting genes: AKR1C3 AMFR ATXN3 BARD1 BFAR BIRC2 BIRC8 BRCA1 CADPS2 CBL CHFR CNOT4 DNMT3B DTX3 DTX3L DZIP3 EED ELOC FANCL LRSAM1 MAP3K1 MAPT MARCHF3 MARCHF5 MGRN1 MIB1 MID1 MKRN1 MKRN3 MUL1 PJA2 POLR2C PSTPIP1 RFWD3 RMND5B RNF10 RNF103 RNF111 RNF114 RNF115 RNF123 RNF125 RNF138 RNF14 RNF150 RNF152 RNF165 RNF166 RNF167 RNF183 RNF185 RNF2 RNF26 RNF31 RNF4 RNF5 RNF8 ROPN1 SNCA STUB1 TOPORS TRIM17 TRIM2 TRIM23 TRIM27 TRIM31 TRIM35 TRIM39 TRIM5 TRIM59 TRIM8 UBA1 UBOX5 UFM1 UHRF2 USHBP1 XIAP ZNRF1 ZNRF2 ZNRF4	15 interacting genes: BCL2 CASP10 CASP8 CPPED1 PRKACA SHISA9 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2N UBE2U UBE2W
Entrez ID		55284	51283
HPRD ID		07724	16548
Ensembl ID		ENSG00000104343	ENSG00000103429
Uniprot IDs		Q96B02 Q96FI0 X6REH9	H3BMP2 Q9NZS9
PDB IDs		2A7L 2MT6
Enriched GO Terms of Interacting Partners?
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