STEAP3 and SETD7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		STEAP3	SETD7
Description		STEAP3 metalloreductase	SET domain containing 7, histone lysine methyltransferase
Image
GO Annotations	Cellular Component	Cytoplasm Endosome Multivesicular Body Plasma Membrane Endosome Membrane Integral Component Of Membrane	Nucleoplasm Chromosome Nucleolus
	Molecular Function	Protein Binding Cupric Reductase Activity Oxidoreductase Activity, Acting On Metal Ions, NAD Or NADP As Acceptor Metal Ion Binding Ferric-chelate Reductase (NADPH) Activity	P53 Binding Chromatin Binding Protein Binding Protein-lysine N-methyltransferase Activity Histone-lysine N-methyltransferase Activity
	Biological Process	Apoptotic Process Cell Cycle Protein Secretion Copper Ion Import Transferrin Transport Iron Ion Homeostasis	Chromatin Organization Cellular Response To DNA Damage Stimulus Peptidyl-lysine Monomethylation Peptidyl-lysine Dimethylation Histone Lysine Methylation Response To Ethanol Positive Regulation Of Transcription, DNA-templated Regulation Of Histone H3-K9 Methylation Heterochromatin Organization
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release CDC42 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOF GTPase cycle Transferrin endocytosis and recycling	PKMTs methylate histone lysines
Drugs			S-adenosyl-L-homocysteine
Diseases
GWAS		Cocaine dependence ( 23958962) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Renal cell carcinoma x sex interaction ( 31231134)	Diastolic blood pressure in combination therapy (beta blocker and thiazide diuretic) ( 29097388) Ferritin levels ( 33491795) Lean body mass ( 28552196) Salty taste perception in obesity with metabolic syndrome ( 31005965) Serum lycopene concentrations ( 26861389)
Interacting Genes		6 interacting genes: BAD BNIP3L MTDH PKMYT1 SETD7 TPT1	31 interacting genes: A1BG ATG16L1 DNMT1 E2F1 ESR1 H3-3A H3-4 H3C1 H3C14 H4C1 HCFC1 KLF4 L3MBTL1 MDM2 NR2F2 OGT PPP1R12A PRKAR1A RELA RIOK1 SERTAD1 SIL1 SIRT1 SMAD7 SOX2 STAT3 STEAP3 TAF10 TAF7 TP53 TRIM21
Entrez ID		55240	80854
HPRD ID		10285	16226
Ensembl ID		ENSG00000115107	ENSG00000145391
Uniprot IDs		A1P3F0 B8ZZX6 Q658P3	B5MCZ8 D6RJA0 Q8WTS6
PDB IDs		2VNS 2VQ3	1H3I 1MT6 1MUF 1N6A 1N6C 1O9S 1XQH 2F69 3CBM 3CBO 3CBP 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 3OS5 3VUZ 3VV0 4E47 4J7F 4J7I 4J83 4J8O 4JDS 4JLG 5AYF 5EG2 5YLT
Enriched GO Terms of Interacting Partners?
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