STEAP3 and BNIP3L

Number of citations of the paper that reports this interaction (PubMedID 12606722)
27

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		STEAP3	BNIP3L
Description		STEAP3 metalloreductase	BCL2 interacting protein 3 like
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Multivesicular Body Plasma Membrane Endosome Membrane Integral Component Of Membrane	Nucleus Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Cytosol Integral Component Of Membrane Nuclear Speck Intrinsic Component Of Membrane
	Molecular Function	Protein Binding Cupric Reductase Activity Oxidoreductase Activity, Acting On Metal Ions, NAD Or NADP As Acceptor Metal Ion Binding Ferric-chelate Reductase (NADPH) Activity	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Apoptotic Process Cell Cycle Protein Secretion Copper Ion Import Transferrin Transport Iron Ion Homeostasis	Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Macroautophagy Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Defense Response To Virus Negative Regulation Of Cell Death Cellular Response To Hypoxia Mitochondrial Outer Membrane Permeabilization Regulation Of Autophagy Of Mitochondrion Regulation Of Protein Targeting To Mitochondrion
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release CDC42 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOF GTPase cycle Transferrin endocytosis and recycling	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Drugs
Diseases
GWAS		Cocaine dependence ( 23958962) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Renal cell carcinoma x sex interaction ( 31231134)	Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252) Schizophrenia ( 28991256 30285260)
Interacting Genes		6 interacting genes: BAD BNIP3L MTDH PKMYT1 SETD7 TPT1	35 interacting genes: ADIPOQ BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 CYB5B DOK5 DUSP3 ECM1 EWSR1 FATE1 GABARAPL1 GABARAPL2 GBP2 GNB5 HTR2B KEAP1 KLHL23 LDLRAD1 LMNA MALL MAP1LC3A NGFR RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11 TMEM120B TMPRSS4 TNMD
Entrez ID		55240	665
HPRD ID		10285	07288
Ensembl ID		ENSG00000115107	ENSG00000104765
Uniprot IDs		A1P3F0 B8ZZX6 Q658P3	O60238 Q6IBV1
PDB IDs		2VNS 2VQ3
Enriched GO Terms of Interacting Partners?
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