TRIM62 and UBE2L6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM62	UBE2L6
Description		tripartite motif containing 62	ubiquitin conjugating enzyme E2 L6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytosol
	Molecular Function	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding ISG15 Transferase Activity Ubiquitin Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein K27-linked Ubiquitination Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Viral Release From Host Cell Positive Regulation Of Antifungal Innate Immune Response	Protein Polyubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process ISG15-protein Conjugation
Pathways		Interferon gamma signaling	ISG15 antiviral mechanism DDX58/IFIH1-mediated induction of interferon-alpha/beta Termination of translesion DNA synthesis Negative regulators of DDX58/IFIH1 signaling Negative regulators of DDX58/IFIH1 signaling Amyloid fiber formation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756)	Blood protein levels ( 28240269)
Interacting Genes		19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25	40 interacting genes: ARHGDIA ARIH1 ARIH2 CBLC DTX3 FLT3 HERC5 LONRF1 MAP3K1 MID1 MUL1 NEDD4L PJA2 PRKN RBCK1 RBX1 RNF122 RNF125 RNF144A RNF144B RNF150 RNF19A RNF216 RNF25 RNF4 RNF40 RUNX1 SIAH1 SIAH2 SPEN TOPORS TRAF7 TRIM25 TRIM27 TRIM62 TRIM8 UBA1 UBA6 UBA7 UBE3A
Entrez ID		55223	9246
HPRD ID		07697	04867
Ensembl ID		ENSG00000116525	ENSG00000156587
Uniprot IDs		Q9BVG3	O14933
PDB IDs			1WZV 1WZW 2KJH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?