TRIM62 and FAIM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM62	FAIM
Description		tripartite motif containing 62	Fas apoptotic inhibitory molecule
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm
	Molecular Function	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein K27-linked Ubiquitination Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Viral Release From Host Cell Positive Regulation Of Antifungal Innate Immune Response	Apoptotic Process I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Neurogenesis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756)	Blood protein levels ( 30072576) Male-pattern baldness ( 28196072)
Interacting Genes		19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25	9 interacting genes: CDR2L DAPP1 INCA1 LHX3 LMNA SPRY2 TRIM62 ZNF16 ZRANB1
Entrez ID		55223	55179
HPRD ID		07697	16874
Ensembl ID		ENSG00000116525	ENSG00000158234
Uniprot IDs		Q9BVG3	Q9NVQ4
PDB IDs			2KW1 3MX7
Enriched GO Terms of Interacting Partners?
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