RIC8B and CKAP4

		RIC8B	CKAP4
Description		RIC8 guanine nucleotide exchange factor B	cytoskeleton associated protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell Cortex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lipid Droplet Cytosol Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane Nuclear Speck Azurophil Granule Membrane Specific Granule Membrane Cytoplasmic Ribonucleoprotein Granule Lamellar Body Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	G-protein Alpha-subunit Binding Guanyl-nucleotide Exchange Factor Activity	RNA Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Catalytic Activity
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Surfactant metabolism Neutrophil degranulation Post-translational protein phosphorylation RND3 GTPase cycle RND2 GTPase cycle
Drugs
Diseases
GWAS		Adiponectin levels ( 31178129) Brain morphology (MOSTest) ( 32665545) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Night sleep phenotypes ( 27126917) PR interval ( 32439900) Serum alkaline phosphatase levels ( 33547301 33339817) Severe influenza A (H1N1) infection ( 26379185) Social autistic-like traits ( 24133439) Triglyceride levels ( 29083408 32203549 28334899 32154731) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: CKAP4 GNAQ GNAS LRP1	21 interacting genes: ASCC2 ATF4 DKK1 HAMP HCFC2 LINC01554 MLH1 MVP NDUFB7 NKX3-1 OGT PLAT PLXNC1 POLR3B PWP1 RIC8B SLC41A2 THOC7 TSNAX WASHC3 WSCD2
Entrez ID		55188	10970
HPRD ID		16452	16717
Ensembl ID		ENSG00000111785	ENSG00000136026
Uniprot IDs		A0A024RBG9 B7WPL0 Q9NVN3	A0A024RBH2 Q07065
PDB IDs
Enriched GO Terms of Interacting Partners?
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