PNPO and AGTRAP

Number of citations of the paper that reports this interaction (PubMedID 25910212)
170

Data Source:
BioGRID (two hybrid, two hybrid)

		PNPO	AGTRAP
Description		pyridoxamine 5'-phosphate oxidase	angiotensin II receptor associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Pyridoxamine-phosphate Oxidase Activity Protein Binding FMN Binding Pyridoxal Phosphate Binding Protein Homodimerization Activity	Angiotensin Type II Receptor Activity Protein Binding
	Biological Process	Pyridoxine Biosynthetic Process Pyridoxal Phosphate Biosynthetic Process	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways		Vitamins B6 activation to pyridoxal phosphate	Signaling by BRAF and RAF1 fusions
Drugs		Pyridoxal phosphate Flavin mononucleotide Mercaptoethanol
Diseases
GWAS		Body mass index ( 26426971) Generalized epilepsy ( 30531953 22949513)	Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Basophil percentage of white cells ( 32888494) Systolic blood pressure ( 19430483)
Interacting Genes		4 interacting genes: AGTRAP APP CMTM5 LIME1	138 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 ANKS6 AP3M1 APOA4 AQP6 ARAF ARFIP2 ARHGAP1 ATP5F1E BCL2L13 BPIFA2 CAPNS1 CCDC70 CD160 CD79A CELA3A CIAO2A COQ8A CPLX1 CPLX4 CRCT1 CYB5R3 CYBC1 DDA1 DDX55 DGCR6 DIABLO DNAJC1 ECPAS ERGIC3 ETFRF1 FAM114A1 FAM209A FARS2 FASTKD3 FATE1 FFAR2 FGA FHIP1B FNDC9 GABARAPL2 GAD1 GAD2 GDNF GPR152 GPX8 GTF2H1 GTF3C1 H4C7 HARS2 HIBADH HMGB1 HSBP1L1 HSCB HSD17B13 HSFX1 HSFX2 HSPA4 IL7R ISCU KCNK5 KIR2DL3 KIR3DL3 LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MGST3 MIEF1 MIEF2 MMD MRM1 MRPL11 MRRF MTERF3 MUTYH MYG1 NDRG4 NDUFAF3 NFU1 NFYB NKG7 PBX3 PCTP PCYT1A PDHX PIMREG PITPNC1 PNPO POLDIP2 PPIF PRPF18 PTPN9 RAB30 RACK1 RBFA RETREG3 RMDN2 S100B SCAND1 SENP2 SH3GLB1 SLC18A1 SLC7A14 SMG9 SNX1 SPG21 SSX3 SSX5 STAG3L1 STAR STARD4 STMN4 STX1A SUCLA2 SYT16 TBRG4 TCEA2 TCEANC2 TFAM THAP4 TMEM139 TMEM14B TMEM31 TMPPE TPD52L3 TTPA TUBA1B TXN2 UBE2I YARS2 ZFYVE21 ZNF391
Entrez ID		55163	57085
HPRD ID		04476	16379
Ensembl ID		ENSG00000108439	ENSG00000177674
Uniprot IDs		Q9NVS9 V9HW45	Q6RW13
PDB IDs		1NRG 3HY8 6H00
Enriched GO Terms of Interacting Partners?
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