EPN3 and TRIM26

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EPN3	TRIM26
Description		epsin 3	tripartite motif containing 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Endosome Plasma Membrane Clathrin-coated Pit Extrinsic Component Of Plasma Membrane Clathrin Vesicle Coat Clathrin-coated Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome	Cellular_component Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Phospholipid Binding Clathrin Binding EH Domain Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Endocytosis	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Hip index ( 34021172)	Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Hematocrit ( 32888494) LDL cholesterol levels ( 32203549) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401) Neuroticism ( 29255261) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 21926974 22883433 30285260) Squamous cell lung carcinoma ( 28604730) Triglyceride levels ( 32203549) Waist-hip index ( 34021172)
Interacting Genes		11 interacting genes: DAZAP2 FAM168A LAPTM5 LITAF MID1 NTAQ1 RNF11 RNF8 RPS27A TRIM26 UBC	28 interacting genes: BEND7 BIVM DDX41 EPN2 EPN3 INCA1 IRF3 LMNA MACROH2A1 MAGEA6 MIR138-2 MIR18B MNAT1 OTUB2 PHF7 RABEP1 RNF10 RNF126 SUMO2 THAP1 TLE5 TRIM41 UBE2D1 UBE2D2 UBE2D3 USP36 USP39 USP5
Entrez ID		55040	7726
HPRD ID		06272	02901
Ensembl ID		ENSG00000049283	ENSG00000234127
Uniprot IDs		Q9H201	A0A024RCP3 Q12899
PDB IDs
Enriched GO Terms of Interacting Partners?
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