CT55 and KYNU

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CT55	KYNU
Description		cancer/testis antigen 55	kynureninase
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding	Pyridoxal Phosphate Binding Kynureninase Activity Protein Homodimerization Activity 3-hydroxykynureninase Activity
	Biological Process		Tryptophan Catabolic Process Aging NAD Biosynthetic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Quinolinate Biosynthetic Process Response To Interferon-gamma 'de Novo' NAD Biosynthetic Process From Tryptophan Response To Vitamin B6 Anthranilate Metabolic Process L-kynurenine Catabolic Process
Pathways			Tryptophan catabolism
Drugs			Pyridoxal phosphate Alanine m-Hydroxyhippuric acid
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Blood protein levels ( 30072576 29875488 28240269) Cataracts ( 34127677) Empathy quotient ( 29527006) Glomerular filtration rate in chronic kidney disease ( 26420894) Neurological blood protein biomarker levels ( 31320639) Platelet count ( 32888494) Response to SSRI (symptom remission) ( 29160301) Toenail selenium levels ( 25343990)
Interacting Genes		32 interacting genes: BFSP2 BHLHB9 C1orf109 C2CD6 CABP5 CPNE2 DES EXOC7 FAAP20 GFAP KIAA0753 KLC3 KLHL42 KYNU LYPLAL1 MBD3 MEMO1 MEOX2 P4HA3 PAX7 PIH1D2 PRPH SAMD11 SHC3 SNF8 SPG21 TFIP11 TLE5 TXLNB VIM ZNF177 ZNF559-ZNF177	9 interacting genes: CDC42 CT55 CTBP2 FAM86C1P LMO4 MCCD1 MYOZ3 PIP4K2B RASSF3
Entrez ID		54967	8942
HPRD ID		06534	08940
Ensembl ID		ENSG00000169551	ENSG00000115919
Uniprot IDs		Q8WUE5	Q16719
PDB IDs			2HZP 3E9K
Enriched GO Terms of Interacting Partners?
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