KYNU and FAM86C1P

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KYNU	FAM86C1P
Description		kynureninase	family with sequence similarity 86 member C1, pseudogene
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol	Protein-containing Complex
	Molecular Function	Pyridoxal Phosphate Binding Kynureninase Activity Protein Homodimerization Activity 3-hydroxykynureninase Activity	Protein Binding Protein-L-histidine N-tele-methyltransferase Activity
	Biological Process	Tryptophan Catabolic Process Aging NAD Biosynthetic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Quinolinate Biosynthetic Process Response To Interferon-gamma 'de Novo' NAD Biosynthetic Process From Tryptophan Response To Vitamin B6 Anthranilate Metabolic Process L-kynurenine Catabolic Process	Peptidyl-histidine Methylation, To Form Tele-methylhistidine
Pathways		Tryptophan catabolism
Drugs		Pyridoxal phosphate Alanine m-Hydroxyhippuric acid
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Blood protein levels ( 30072576 29875488 28240269) Cataracts ( 34127677) Empathy quotient ( 29527006) Glomerular filtration rate in chronic kidney disease ( 26420894) Neurological blood protein biomarker levels ( 31320639) Platelet count ( 32888494) Response to SSRI (symptom remission) ( 29160301) Toenail selenium levels ( 25343990)
Interacting Genes		9 interacting genes: CDC42 CT55 CTBP2 FAM86C1P LMO4 MCCD1 MYOZ3 PIP4K2B RASSF3	22 interacting genes: ANKS1A BCAS2 C1orf109 CDKN2D CDR2L COL8A1 CRACR2A CSNK2B CTTNBP2 DOK6 GPSM3 HNRNPF KRT26 KYNU MAGED4B PCSK5 POU4F2 SAT1 SMYD1 SPG21 TRAF1 VENTX
Entrez ID		8942	55199
HPRD ID		08940	13337
Ensembl ID		ENSG00000115919
Uniprot IDs		Q16719	Q9NVL1
PDB IDs		2HZP 3E9K
Enriched GO Terms of Interacting Partners?
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