SPDL1 and DNAAF4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		SPDL1	DNAAF4
Description		spindle apparatus coiled-coil protein 1	dynein axonemal assembly factor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Outer Kinetochore Nucleus Microtubule Organizing Center Cytosol	Extracellular Region Nucleus Cytoplasm Centrosome Cytosol Plasma Membrane Neuron Projection Non-motile Cilium Dynein Axonemal Particle
	Molecular Function	Protein Binding Enzyme Binding Kinetochore Binding	Protein Binding Estrogen Receptor Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Metaphase Plate Congression Mitotic Spindle Assembly Checkpoint Signaling Cell Migration Protein Localization To Kinetochore Cell Division	Neuron Migration Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Determination Of Left/right Symmetry Heart Development Regulation Of Intracellular Estrogen Receptor Signaling Pathway Outer Dynein Arm Assembly Inner Dynein Arm Assembly Regulation Of Proteasomal Protein Catabolic Process
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Bipolar disorder x sex interaction ( 34099189)
Interacting Genes		10 interacting genes: CA8 CEP126 DNAAF4 GPS2 ITSN1 PPP1R18 RTP5 TRAF4 USP15 USP45	13 interacting genes: BANF2 CRACR2B EXOC5 GCOM1 HSPA1A KDM1A KRT13 MCC PRTG SPDL1 STUB1 TRIM23 WDR72
Entrez ID		54908	161582
HPRD ID		08623	10568
Ensembl ID		ENSG00000040275	ENSG00000256061
Uniprot IDs		Q96EA4	A0A0S2Z5Z4 Q8WXU2
PDB IDs
Enriched GO Terms of Interacting Partners?
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