NECAB2 and BEX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		NECAB2	BEX2
Description		N-terminal EF-hand calcium binding protein 2	brain expressed X-linked 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Axon Dendrite	Nucleus Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane	Apoptotic Process Cell Cycle Signal Transduction Regulation Of Apoptotic Process Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)
Interacting Genes		93 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C19orf25 C1orf109 C1orf216 CAGE1 CAPN3 CARD9 CCDC121 CCDC146 CCDC153 CCDC33 CCNK CDC37 CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L DTNBP1 DYNC1I2 EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FAM161B FANCG FMR1 FXR1 FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 INTS10 ISCU KANK2 KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 MSGN1 MTMR9 MYO15B MYPOP NECAB1 NEK6 NIP7 NOC4L NTAQ1 ODAD3 ODAD4 OIP5 PATJ PCM1 PICK1 POLR2C PRKAA2 PRPF18 PSMA1 PUS10 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SMARCA2 SMARCD1 SNAPIN SOGA1 SSC5D TCEA2 TEX11 TRIM59 TRIML2 TSC1 TTR USHBP1 USP7 VTA1 ZNF655	92 interacting genes: AKAP9 AURKA BCAR3 BHLHB9 BLZF1 BORCS6 BRMS1 CALCOCO2 CCDC197 CCDC57 CCDC85B CCDC88B CDR2 CEP70 COG4 CTAG1A CTAG1B CYSRT1 EXOC8 FGFR2 FSD2 FST HSF2BP HSPB2 HSPB2-C11orf52 KLHL20 KNSTRN KRT15 KRT19 KRT27 KRT31 KRT34 KRT38 KRT39 KRT40 KRT6A KRT75 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP3-3 KRTAP4-12 KRTAP5-9 KRTAP6-2 KRTAP6-3 LCN2 LDOC1 LMO2 LZTS2 MAGEA11 MAGEA2 MAGEA2B MAGEA4 MDFI MIPOL1 MKRN3 MORN3 MRPL38 MSS51 MTUS2 NECAB2 NFKBID OIP5 OMP PIK3CA PLA2G10 PLEKHG4 PNMA1 PPM1D PRDM14 PTPN11 ROPN1L SERTAD3 SPRED1 SPRY3 SSX2IP SYCE1 TACC3 TRAF1 TRAF2 TRIM27 TRIM42 TRIM69 TRIM73 TRIP6 USHBP1 VPS28 ZDHHC17 ZNF19
Entrez ID		54550	84707
HPRD ID		13263	06484
Ensembl ID		ENSG00000103154	ENSG00000133134
Uniprot IDs		Q7Z6G3	Q9BXY8
PDB IDs
Enriched GO Terms of Interacting Partners?
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