NECAB2 and VTA1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NECAB2	VTA1
Description		N-terminal EF-hand calcium binding protein 2	vesicle trafficking 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Axon Dendrite	Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane	Protein Transport Macroautophagy Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Multivesicular Body Sorting Pathway ESCRT III Complex Disassembly
Pathways			Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)	Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) FEV1 ( 30804560) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578) Retinal vascular caliber ( 21060863) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes		93 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C19orf25 C1orf109 C1orf216 CAGE1 CAPN3 CARD9 CCDC121 CCDC146 CCDC153 CCDC33 CCNK CDC37 CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L DTNBP1 DYNC1I2 EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FAM161B FANCG FMR1 FXR1 FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 INTS10 ISCU KANK2 KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 MSGN1 MTMR9 MYO15B MYPOP NECAB1 NEK6 NIP7 NOC4L NTAQ1 ODAD3 ODAD4 OIP5 PATJ PCM1 PICK1 POLR2C PRKAA2 PRPF18 PSMA1 PUS10 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SMARCA2 SMARCD1 SNAPIN SOGA1 SSC5D TCEA2 TEX11 TRIM59 TRIML2 TSC1 TTR USHBP1 USP7 VTA1 ZNF655	22 interacting genes: APP BEX3 CBS CCNC CDK4 CHMP1A CHMP1B CHMP5 DPPA2 ERBB3 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 RABAC1 RPIA TEAD4 ZBTB16 ZNRD2
Entrez ID		54550	51534
HPRD ID		13263	09855
Ensembl ID		ENSG00000103154	ENSG00000009844
Uniprot IDs		Q7Z6G3	A0A087WY55 Q9NP79
PDB IDs			2LXL 2LXM 4TXP 4TXQ 4TXR 4U7E
Enriched GO Terms of Interacting Partners?
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