ATP6AP1 and LARP1

		ATP6AP1	LARP1
Description		ATPase H+ transporting accessory protein 1	La ribonucleoprotein 1, translational regulator
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Endosome Membrane Integral Component Of Membrane Proton-transporting Two-sector ATPase Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Proton-transporting V-type ATPase, V1 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Cytoplasm Cytoplasmic Stress Granule Membrane Polysomal Ribosome
	Molecular Function	Protein Binding ATP Binding Small GTPase Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Eukaryotic Initiation Factor 4E Binding Translation Activator Activity Translation Initiation Factor Binding Ribosomal Small Subunit Binding Cadherin Binding MRNA 5'-UTR Binding
	Biological Process	Cellular Iron Ion Homeostasis Regulation Of Cellular PH Cellular Response To Increased Oxygen Levels Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Bone Resorption PH Reduction Positive Regulation Of Exocytosis Establishment Of Organelle Localization Positive Regulation Of ERK1 And ERK2 Cascade Proton Transmembrane Transport Positive Regulation Of Osteoclast Development	Translational Initiation Cell Population Proliferation Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Macroautophagy Negative Regulation Of Translation TOR Signaling TORC1 Signaling Positive Regulation Of Viral Genome Replication Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation MRNA Stabilization Cellular Response To Rapamycin Response To Amino Acid Starvation
Pathways		Insulin receptor recycling RHOA GTPase cycle Transferrin endocytosis and recycling Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS			Chin dimples ( 27182965) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Monobrow ( 27182965) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		11 interacting genes: ABCD1 ANG CETN2 CTAG1B ERBB2 HBA1 LARP1 NR1I2 NT5E OGT RHOU	13 interacting genes: ATP6AP1 BCL2L1 CSNK2A1 KASH5 LCP2 PPID PPL SRPK1 TNNT1 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		537	23367
HPRD ID		02184	11225
Ensembl ID		ENSG00000071553	ENSG00000155506
Uniprot IDs		A0A0C4DGX8 A0A384MQW4 Q15904	Q6PKG0
PDB IDs		6WLW 6WM2 6WM3 6WM4	4ZC4 5C0V 5V4R 5V7C 5V87 6PW3
Enriched GO Terms of Interacting Partners?
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