ATP6AP1 and CETN2

		ATP6AP1	CETN2
Description		ATPase H+ transporting accessory protein 1	centrin 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Endosome Membrane Integral Component Of Membrane Proton-transporting Two-sector ATPase Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Proton-transporting V-type ATPase, V1 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Nucleoplasm Centrosome Centriole Cytosol Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex 9+2 Motile Cilium
	Molecular Function	Protein Binding ATP Binding Small GTPase Binding	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding
	Biological Process	Cellular Iron Ion Homeostasis Regulation Of Cellular PH Cellular Response To Increased Oxygen Levels Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Bone Resorption PH Reduction Positive Regulation Of Exocytosis Establishment Of Organelle Localization Positive Regulation Of ERK1 And ERK2 Cascade Proton Transmembrane Transport Positive Regulation Of Osteoclast Development	Mitotic Cell Cycle Nucleotide-excision Repair Centriole Replication Spermatogenesis Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division
Pathways		Insulin receptor recycling RHOA GTPase cycle Transferrin endocytosis and recycling Ion channel transport	Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2
Drugs		Tiludronic acid
Diseases
GWAS			Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		11 interacting genes: ABCD1 ANG CETN2 CTAG1B ERBB2 HBA1 LARP1 NR1I2 NT5E OGT RHOU	10 interacting genes: ARSA ATP6AP1 CCP110 DDX3X PNMA5 POC5 PRMT6 SFI1 SGSM1 XPC
Entrez ID		537	1069
HPRD ID		02184	02051
Ensembl ID		ENSG00000071553	ENSG00000147400
Uniprot IDs		A0A0C4DGX8 A0A384MQW4 Q15904	P41208
PDB IDs		6WLW 6WM2 6WM3 6WM4	1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH
Enriched GO Terms of Interacting Partners?
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