PLP2 and CYBRD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLP2	CYBRD1
Description		proteolipid protein 2	cytochrome b reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome
	Molecular Function	Protein Binding Ion Transmembrane Transporter Activity Chemokine Binding	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Metal Ions Identical Protein Binding Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity Transmembrane Monodehydroascorbate Reductase Activity
	Biological Process	Ion Transport Chemotaxis Cytokine-mediated Signaling Pathway Ion Transmembrane Transport	Cellular Iron Ion Homeostasis Response To Iron Ion Reductive Iron Assimilation Iron Ion Homeostasis Transmembrane Transport Ascorbate Homeostasis
Pathways			Iron uptake and transport
Drugs
Diseases
GWAS		Platelet distribution width ( 32888494)	Body fat distribution (arm fat ratio) ( 30664634) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Pulse pressure ( 30224653) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		75 interacting genes: AQP2 AQP3 AQP8 ARFIP2 ASGR2 ATP5PF BCAP31 BIK BNIP3 CCR1 CD53 CD79A CERS4 CIAO2A CLDN5 CLN8 CPLX4 CRB3 CREB3L1 CYB561 CYBC1 CYBRD1 DARS2 DLGAP4 DNAJC1 EBP ELOVL5 ELP1 EVI2A FAM209A FAM210B FATE1 FCER1G FNDC9 GPR151 GPX8 HSBP1L1 HSD17B11 HSD17B13 KASH5 LHFPL1 LHFPL5 LMNA LRRC4C MGST3 NDRG4 PACC1 PDZK1IP1 PIGP PSCA PTGES PVR RAB10 REEP4 RETREG3 RNF5 SAR1A SCN3B SGPL1 SHBG SLC14A2 SLC18A1 SLC2A13 SLC35C2 SPG21 SPN THAP4 TM4SF19 TMEM14B TMEM31 TMEM51 TMEM79 TMPRSS2 TMX2 VKORC1	20 interacting genes: CREB3 FKBP8 GIMAP5 GOSR2 HMOX1 LMNA LPAR3 NEDD4L PLP2 RABAC1 SEC22A SERP1 SERP2 STX4 STX7 TMEM120A TMEM65 VAPA VAPB ZFPL1
Entrez ID		5355	79901
HPRD ID		02121	05764
Ensembl ID		ENSG00000102007	ENSG00000071967
Uniprot IDs		A0A024QYW3 Q04941	Q53TN4
PDB IDs			5ZLE 5ZLG
Enriched GO Terms of Interacting Partners?
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