PLP2 and THAP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLP2	THAP4
Description		proteolipid protein 2	THAP domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Cellular_component
	Molecular Function	Protein Binding Ion Transmembrane Transporter Activity Chemokine Binding	DNA Binding Protein Binding Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding
	Biological Process	Ion Transport Chemotaxis Cytokine-mediated Signaling Pathway Ion Transmembrane Transport	Tyrosine Metabolic Process Nitrate Metabolic Process
Pathways
Drugs
Diseases
GWAS		Platelet distribution width ( 32888494)	Brain structure ( 20171287) Hip circumference adjusted for BMI ( 34021172) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		75 interacting genes: AQP2 AQP3 AQP8 ARFIP2 ASGR2 ATP5PF BCAP31 BIK BNIP3 CCR1 CD53 CD79A CERS4 CIAO2A CLDN5 CLN8 CPLX4 CRB3 CREB3L1 CYB561 CYBC1 CYBRD1 DARS2 DLGAP4 DNAJC1 EBP ELOVL5 ELP1 EVI2A FAM209A FAM210B FATE1 FCER1G FNDC9 GPR151 GPX8 HSBP1L1 HSD17B11 HSD17B13 KASH5 LHFPL1 LHFPL5 LMNA LRRC4C MGST3 NDRG4 PACC1 PDZK1IP1 PIGP PSCA PTGES PVR RAB10 REEP4 RETREG3 RNF5 SAR1A SCN3B SGPL1 SHBG SLC14A2 SLC18A1 SLC2A13 SLC35C2 SPG21 SPN THAP4 TM4SF19 TMEM14B TMEM31 TMEM51 TMEM79 TMPRSS2 TMX2 VKORC1	42 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6
Entrez ID		5355	51078
HPRD ID		02121	11630
Ensembl ID		ENSG00000102007	ENSG00000176946
Uniprot IDs		A0A024QYW3 Q04941	Q8WY91
PDB IDs			3IA8
Enriched GO Terms of Interacting Partners?
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