FXYD3 and MGST1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FXYD3	MGST1
Description		FXYD domain containing ion transport regulator 3	microsomal glutathione S-transferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Nucleus Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Azurophil Granule Membrane Apical Part Of Cell
	Molecular Function	Chloride Channel Activity Sodium Channel Regulator Activity	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding Glutathione Binding
	Biological Process	Potassium Ion Transport Sodium Ion Transport Chloride Transport Regulation Of Sodium Ion Transmembrane Transporter Activity	Response To Xenobiotic Stimulus Response To Organonitrogen Compound Response To Lipopolysaccharide Leydig Cell Differentiation Glutathione Transport Cellular Response To Lipid Hydroperoxide Cellular Oxidant Detoxification
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Glutathione conjugation Aflatoxin activation and detoxification Neutrophil degranulation
Drugs			Glutathione Glutathione disulfide
Diseases
GWAS			Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Bell's palsy ( 33602968) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Household income (MTAG) ( 31844048) Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Visceral fat ( 22589738)
Interacting Genes		64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3	8 interacting genes: EGF FXYD3 FZD7 LTC4S NELFB SIGLEC12 TNFRSF10C VIP
Entrez ID		5349	4257
HPRD ID		05410	00705
Ensembl ID		ENSG00000089356	ENSG00000008394
Uniprot IDs		Q14802	A0A024RAX2 P10620
PDB IDs
Enriched GO Terms of Interacting Partners?
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