PGR and RBM23

Number of citations of the paper that reports this interaction (PubMedID 15694343)
79

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		PGR	RBM23
Description		progesterone receptor	RNA binding motif protein 23
Image
GO Annotations	Cellular Component	Chromatin Nucleoplasm Mitochondrial Outer Membrane Cytosol	Nucleus Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Steroid Hormone Receptor Activity Nuclear Receptor Activity Steroid Binding Protein Binding Zinc Ion Binding Enzyme Binding Identical Protein Binding ATPase Binding	RNA Binding Protein Binding
	Biological Process	Ovulation From Ovarian Follicle Epithelial Cell Maturation Regulation Of Transcription By RNA Polymerase II Signal Transduction Cell-cell Signaling Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Intracellular Steroid Hormone Receptor Signaling Pathway Paracrine Signaling Positive Regulation Of Transcription By RNA Polymerase II Lung Alveolus Development Regulation Of Epithelial Cell Proliferation Progesterone Receptor Signaling Pathway Tertiary Branching Involved In Mammary Gland Duct Morphogenesis	MRNA Processing RNA Splicing Positive Regulation Of Transcription, DNA-templated Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Nuclear signaling by ERBB4 HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Nuclear Receptor transcription pathway SUMOylation of intracellular receptors Estrogen-dependent gene expression
Drugs		Etonogestrel Desogestrel Megestrol acetate Levonorgestrel Dydrogesterone Progesterone Spironolactone Lindane Fluticasone propionate Medroxyprogesterone acetate Mitotane Norethisterone Mometasone Ethynodiol diacetate Mifepristone Norgestimate Drospirenone Danazol Oxybenzone Allylestrenol Phthalic Acid Metribolone Tanaproget Telapristone acetate Asoprisnil Norelgestromin Gestodene Hydroxyprogesterone caproate Ulipristal Fluticasone furoate Dienogest Medrogestone Norgestrel Homosalate Enzacamene Gestrinone Darolutamide Demegestone Fluticasone Mometasone furoate Segesterone acetate
Diseases
GWAS		Diastolic blood pressure ( 30224653) Length of menstrual cycle ( 30202859) Menarche (age at onset) ( 25231870) Severity of nausea and vomiting of pregnancy ( 29563502)	Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical amyloid beta load ( 29860282) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		55 interacting genes: ANP32A APEX2 ARID1A ATM BATF3 BCAS2 BMI1 BRCA1 CCNA1 CCNA2 CDC25B CDK2 COPS5 CSNK2A1 CUEDC2 DAP3 DDX10 DDX54 DNAJA1 ESR1 FKBP5 HMGB1 HMGB2 HSPA1A JDP2 KAT2B KLF9 NCOA1 NCOA3 NR0B1 PIAS1 PIAS2 PIAS3 POU2F1 POU2F2 PRKDC PRMT2 RBM23 RBM39 RELA RNF4 SGTA SMARCD1 SMARCE1 SNW1 SORBS1 SRC TAF1B TDG TRIM24 UBE3A UBR5 XRCC5 XRCC6 ZBTB17	32 interacting genes: BHLHE40 CDK6 CEP126 CHERP ESR1 FAM9B FBXO7 GTF3C1 KHDC4 MAGEA11 MAGED1 MED31 OGT PGR POLA2 PRMT5 PRR20A PRR20B PRR20C PRR20D PRR20E PTN QKI RBFOX2 RBM25 RBM39 RBM4 RPA1 SRPK1 SRPK2 TRIM27 TUBA4A
Entrez ID		5241	55147
HPRD ID		07077	15227
Ensembl ID		ENSG00000082175	ENSG00000100461
Uniprot IDs		P06401	A0A0S2Z5D9 A0A0S2Z5I1 A0A0S2Z5J3 B7Z8M4 G3XAP0 Q86U06
PDB IDs		1A28 1E3K 1SQN 1SR7 1ZUC 2C7A 2OVH 2OVM 2W8Y 3D90 3G8O 3HQ5 3KBA 3ZR7 3ZRA 3ZRB 4A2J 4APU 4OAR 5CC0	2CQ4 2DNZ
Enriched GO Terms of Interacting Partners?
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