HiPPIP
Home
About
SZ Genes
People
Help
Advanced Search
PGR and HSPA1A
Number of citations of the paper that reports this interaction (PubMedID
11809754
)
48
Data Source:
BioGRID
(pull down)
PGR
HSPA1A
Description
progesterone receptor
heat shock protein family A (Hsp70) member 1A
Image
GO Annotations
Cellular Component
Chromatin
Nucleoplasm
Mitochondrial Outer Membrane
Cytosol
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Endoplasmic Reticulum
Centrosome
Centriole
Cytosol
Plasma Membrane
Focal Adhesion
Inclusion Body
Aggresome
Nuclear Speck
Vesicle
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Blood Microparticle
Ficolin-1-rich Granule Lumen
Ribonucleoprotein Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Coactivator Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Steroid Hormone Receptor Activity
Nuclear Receptor Activity
Steroid Binding
Protein Binding
Zinc Ion Binding
Enzyme Binding
Identical Protein Binding
ATPase Binding
Virus Receptor Activity
G Protein-coupled Receptor Binding
Transcription Corepressor Activity
RNA Binding
Signaling Receptor Binding
Protein Binding
ATP Binding
ATP Hydrolysis Activity
Enzyme Binding
Heat Shock Protein Binding
Denatured Protein Binding
Ubiquitin Protein Ligase Binding
Histone Deacetylase Binding
Protein Folding Chaperone
Cadherin Binding
Protein N-terminus Binding
Unfolded Protein Binding
Misfolded Protein Binding
C3HC4-type RING Finger Domain Binding
Disordered Domain Specific Binding
Protein Disaggregase Activity
Biological Process
Ovulation From Ovarian Follicle
Epithelial Cell Maturation
Regulation Of Transcription By RNA Polymerase II
Signal Transduction
Cell-cell Signaling
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Intracellular Steroid Hormone Receptor Signaling Pathway
Paracrine Signaling
Positive Regulation Of Transcription By RNA Polymerase II
Lung Alveolus Development
Regulation Of Epithelial Cell Proliferation
Progesterone Receptor Signaling Pathway
Tertiary Branching Involved In Mammary Gland Duct Morphogenesis
MRNA Catabolic Process
Response To Unfolded Protein
Lysosomal Transport
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Regulation Of Cell Death
Vesicle-mediated Transport
Negative Regulation Of Cell Growth
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Protein Ubiquitination
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of RNA Splicing
Cellular Response To Oxidative Stress
Cellular Response To Heat
Cellular Response To Unfolded Protein
Protein Refolding
Negative Regulation Of Apoptotic Process
Positive Regulation Of Erythrocyte Differentiation
ATP Metabolic Process
Viral Entry Into Host Cell
Protein Stabilization
Chaperone Cofactor-dependent Protein Refolding
Positive Regulation Of NF-kappaB Transcription Factor Activity
Chaperone-mediated Protein Complex Assembly
Negative Regulation Of Cell Death
Cellular Heat Acclimation
Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Positive Regulation Of Microtubule Nucleation
Negative Regulation Of Inclusion Body Assembly
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitotic Spindle Assembly
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Endoribonuclease Activity
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Nuclear signaling by ERBB4
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Estrogen-dependent gene expression
Viral RNP Complexes in the Host Cell Nucleus
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Attenuation phase
HSF1-dependent transactivation
AUF1 (hnRNP D0) binds and destabilizes mRNA
Neutrophil degranulation
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Attenuation phase
HSF1-dependent transactivation
Neutrophil degranulation
Drugs
Etonogestrel
Desogestrel
Megestrol acetate
Levonorgestrel
Dydrogesterone
Progesterone
Spironolactone
Lindane
Fluticasone propionate
Medroxyprogesterone acetate
Mitotane
Norethisterone
Mometasone
Ethynodiol diacetate
Mifepristone
Norgestimate
Drospirenone
Danazol
Oxybenzone
Allylestrenol
Phthalic Acid
Metribolone
Tanaproget
Telapristone acetate
Asoprisnil
Norelgestromin
Gestodene
Hydroxyprogesterone caproate
Ulipristal
Fluticasone furoate
Dienogest
Medrogestone
Norgestrel
Homosalate
Enzacamene
Gestrinone
Darolutamide
Demegestone
Fluticasone
Mometasone furoate
Segesterone acetate
Diseases
GWAS
Diastolic blood pressure (
30224653
)
Length of menstrual cycle (
30202859
)
Menarche (age at onset) (
25231870
)
Severity of nausea and vomiting of pregnancy (
29563502
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Inflammatory bowel disease (
28067908
)
Schizophrenia (
30285260
)
Systemic lupus erythematosus (
32771030
)
Ulcerative colitis (
28067908
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
55 interacting genes:
ANP32A
APEX2
ARID1A
ATM
BATF3
BCAS2
BMI1
BRCA1
CCNA1
CCNA2
CDC25B
CDK2
COPS5
CSNK2A1
CUEDC2
DAP3
DDX10
DDX54
DNAJA1
ESR1
FKBP5
HMGB1
HMGB2
HSPA1A
JDP2
KAT2B
KLF9
NCOA1
NCOA3
NR0B1
PIAS1
PIAS2
PIAS3
POU2F1
POU2F2
PRKDC
PRMT2
RBM23
RBM39
RELA
RNF4
SGTA
SMARCD1
SMARCE1
SNW1
SORBS1
SRC
TAF1B
TDG
TRIM24
UBE3A
UBR5
XRCC5
XRCC6
ZBTB17
91 interacting genes:
AIFM1
AIMP2
APAF1
APEX1
APOB
ATXN1
BAG1
BAG2
BAG3
BAG4
BCL2
BRSK1
CACNA1E
CDK9
CFAP52
DAPP1
DNAAF4
DNAJA2
DNAJA3
DNAJB1
DNAJB11
DNAJC3
EGFR
EIF2AK2
ERBB2
ERBB3
FANCC
FOS
GPR37
GRIN1
GRIN2D
HAP1
HCFC1
HEMGN
HIVEP1
HMGA1
HSBP1
HSF1
HSPA8
HSPBP1
IKBKG
IL3
INS
KRT18
KRT7
MAP3K5
MAPRE1
METTL21A
MOS
MSR1
NQO1
NR3C1
OGT
PEX5
PGR
PLG
POT1
PPP1R15A
PRKCA
PSMC5
PTGES3
PTMA
PTPRF
RAP1A
RAPGEF2
RHOA
SAE1
SLC13A1
SLC5A1
SNCB
SNRK
SOX9
ST13
STIP1
STUB1
SUMO2
TCERG1
TGM2
TOMM70
TP53
TRIAP1
TRIM24
TRIM38
TSSK6
TTC1
UBE2D3
XIAP
YWHAB
YWHAG
YWHAQ
YWHAZ
Entrez ID
5241
3303
HPRD ID
07077
00774
Ensembl ID
ENSG00000082175
ENSG00000204389
Uniprot IDs
P06401
A8K5I0
B3KTT5
P0DMV8
P0DMV9
PDB IDs
1A28
1E3K
1SQN
1SR7
1ZUC
2C7A
2OVH
2OVM
2W8Y
3D90
3G8O
3HQ5
3KBA
3ZR7
3ZRA
3ZRB
4A2J
4APU
4OAR
5CC0
1HJO
1S3X
1XQS
2E88
2E8A
2LMG
3A8Y
3ATU
3ATV
3AY9
3D2E
3D2F
3JXU
3LOF
3Q49
4IO8
4J8F
4PO2
4WV5
4WV7
5AQW
5AQX
5AQY
5AQZ
5AR0
5BN8
5BN9
5BPL
5BPM
5BPN
5GJJ
5MKR
5MKS
5XI9
5XIR
6FDT
6FHK
6G3R
6G3S
6JPV
6K39
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?