LSR and MAPKAPK5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		LSR	MAPKAPK5
Description		lipolysis stimulated lipoprotein receptor	MAPK activated protein kinase 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Chylomicron Tricellular Tight Junction Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function		P53 Binding Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity MAP Kinase Kinase Activity Protein Binding Calmodulin Binding ATP Binding Calcium-dependent Protein Serine/threonine Kinase Activity Mitogen-activated Protein Kinase Binding Protein Serine Kinase Activity
	Biological Process	Liver Development Maintenance Of Blood-brain Barrier Establishment Of Blood-brain Barrier Establishment Of Skin Barrier Protein Localization To Tricellular Tight Junction Tricellular Tight Junction Assembly	MAPK Cascade Regulation Of Translation Signal Transduction Ras Protein Signal Transduction Peptidyl-serine Phosphorylation Negative Regulation Of TOR Signaling Positive Regulation Of Telomere Maintenance Via Telomerase Intracellular Signal Transduction Protein Autophosphorylation Positive Regulation Of Telomerase Activity Cellular Senescence Stress-induced Premature Senescence Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Telomere Capping
Pathways		LDL clearance VLDL clearance	Oxidative Stress Induced Senescence MAPK6/MAPK4 signaling Regulation of TP53 Activity through Phosphorylation
Drugs			Fostamatinib
Diseases
GWAS		Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) ( 33208821) Red blood cell count ( 27863252)	Adult body size ( 32376654) Body mass index ( 26426971) Coffee consumption ( 29367735) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mean spheric corpuscular volume ( 32888494) Psoriasis ( 28537254) Spleen volume ( 34128465) Tea consumption ( 33080986)
Interacting Genes		4 interacting genes: MAPKAPK5 OGT RARG YWHAG	30 interacting genes: ATF2 CDCA8 EEF2K EIF4E EIF4EBP1 GYS1 HMGB1 HSPB1 HSPB2 JUN LSR MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK4 MAPK6 MAPK9 MBP MYH11 PARK7 PLA2G4A RPL13 SRPK1 SRPK2 TAB1 TP53 ZNF282 ZNF576
Entrez ID		51599	8550
HPRD ID		17283	09467
Ensembl ID		ENSG00000105699	ENSG00000089022
Uniprot IDs		Q86X29	Q8IW41
PDB IDs
Enriched GO Terms of Interacting Partners?
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