EVL and DNMBP

Number of citations of the paper that reports this interaction (PubMedID 14506234)
68

Data Source:
HPRD (in vitro, two hybrid)

		EVL	DNMBP
Description		Enah/Vasp-like	dynamin binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium	Golgi Apparatus Golgi Stack Cytosol Cytoskeleton Cell-cell Junction Synapse Presynapse
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly	Aging Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins	CDC42 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)	Stent thrombosis in response to clopidogrel treatment ( 32472697)
Interacting Genes		45 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP ATG2B BDKRB1 BEGAIN C14orf132 CKB CRKL DNMBP ENAH F11R FXR1 FXR2 FYB1 FYN GSKIP HCK HTT KRT17 KRT34 LRP1B LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SH3RF1 SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17 ZNF655 ZYX	20 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 VASP WASF1 WASL WIPF2
Entrez ID		51466	23268
HPRD ID		10942	10918
Ensembl ID		ENSG00000196405	ENSG00000107554
Uniprot IDs		A0A024R6K5 Q9UI08	A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7
PDB IDs			1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?
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