DNMBP and CYFIP2

Number of citations of the paper that reports this interaction (PubMedID 14506234)
68

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		DNMBP	CYFIP2
Description		dynamin binding protein	cytoplasmic FMR1 interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Golgi Stack Cytosol Cytoskeleton Cell-cell Junction Synapse Presynapse	Nucleus Cytoplasm Cytosol Membrane SCAR Complex Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	RNA 7-methylguanosine Cap Binding Protein Binding Small GTPase Binding
	Biological Process	Aging Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction	Cell Morphogenesis Apoptotic Process Regulation Of Actin Filament Polymerization Positive Regulation Of Proteolysis Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Dendrite Extension Cell-cell Adhesion
Pathways		CDC42 GTPase cycle	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs RAC1 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Stent thrombosis in response to clopidogrel treatment ( 32472697)	Alanine aminotransferase levels ( 33547301) Asthma ( 31959851 34103634 32296059) Daytime sleep phenotypes ( 27126917) FEV1 ( 30804560) Gamma glutamyl transferase levels ( 29403010 33339817) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lung function (FEV1/FVC) ( 28166213 30804560) Peak expiratory flow ( 30804560) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577)
Interacting Genes		20 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 VASP WASF1 WASL WIPF2	23 interacting genes: ABI1 ABI3 APBB1 BIRC3 BRK1 DNMBP F2RL1 FMR1 FXR1 FXR2 GAS7 MTDH NCK1 NCKAP1 OXTR PLG PRPF40A SMAD4 TCERG1 WASF1 WASF2 YWHAG ZC3H12A
Entrez ID		23268	26999
HPRD ID		10918	07556
Ensembl ID		ENSG00000107554	ENSG00000055163
Uniprot IDs		A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7	B7Z8N7 E7EVJ5 Q96F07
PDB IDs		1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?
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