DNAJC27 and IFT172

		DNAJC27	IFT172
Description		DnaJ heat shock protein family (Hsp40) member C27	intraflagellar transport 172
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Sperm Midpiece Sperm Principal Piece Ciliary Tip Sperm Cytoplasmic Droplet Extracellular Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of MAPK Export From Nucleus	Neural Tube Closure Heart Looping Notch Signaling Pathway Smoothened Signaling Pathway Brain Development Epidermis Development Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Cytoplasmic Microtubule Organization Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Smoothened Signaling Pathway Embryonic Camera-type Eye Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Roof Of Mouth Development Limb Development Cilium Assembly Bone Development Hindgut Development Left/right Axis Specification Non-motile Cilium Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Body mass index ( 22344219 26426971 28892062) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 28067908) Height ( 20881960 31562340) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Obese vs. thin ( 30677029) Obesity (extreme) ( 30677029) Pre-treatment viral load in HIV-1 infection ( 31219150) Pubertal anthropometrics ( 23449627) Type 1 diabetes ( 21980299)	Calcium levels ( 20705733) Chronic kidney disease ( 20383146) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Total cholesterol levels ( 30718733)
Interacting Genes		2 interacting genes: IFT172 RAB10	6 interacting genes: DNAJC27 EFR3B LHX3 LHX4 RAB10 TMEM214
Entrez ID		51277	26160
HPRD ID		15221	09576
Ensembl ID		ENSG00000115137	ENSG00000138002
Uniprot IDs		Q9NZQ0	A0A6Q8PGJ2 Q9UG01
PDB IDs		2YS8
Enriched GO Terms of Interacting Partners?
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