IFT172 and DNAJC27

		IFT172	DNAJC27
Description		intraflagellar transport 172	DnaJ heat shock protein family (Hsp40) member C27
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Sperm Midpiece Sperm Principal Piece Ciliary Tip Sperm Cytoplasmic Droplet Extracellular Vesicle	Nucleus
	Molecular Function		GTPase Activity Protein Binding GTP Binding
	Biological Process	Neural Tube Closure Heart Looping Notch Signaling Pathway Smoothened Signaling Pathway Brain Development Epidermis Development Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Cytoplasmic Microtubule Organization Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Smoothened Signaling Pathway Embryonic Camera-type Eye Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Roof Of Mouth Development Limb Development Cilium Assembly Bone Development Hindgut Development Left/right Axis Specification Non-motile Cilium Assembly	Intracellular Protein Transport Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of MAPK Export From Nucleus
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Calcium levels ( 20705733) Chronic kidney disease ( 20383146) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Total cholesterol levels ( 30718733)	Body mass index ( 22344219 26426971 28892062) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 28067908) Height ( 20881960 31562340) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Obese vs. thin ( 30677029) Obesity (extreme) ( 30677029) Pre-treatment viral load in HIV-1 infection ( 31219150) Pubertal anthropometrics ( 23449627) Type 1 diabetes ( 21980299)
Interacting Genes		6 interacting genes: DNAJC27 EFR3B LHX3 LHX4 RAB10 TMEM214	2 interacting genes: IFT172 RAB10
Entrez ID		26160	51277
HPRD ID		09576	15221
Ensembl ID		ENSG00000138002	ENSG00000115137
Uniprot IDs		A0A6Q8PGJ2 Q9UG01	Q9NZQ0
PDB IDs			2YS8
Enriched GO Terms of Interacting Partners?
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