HSD17B11 and TMEM203

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSD17B11	TMEM203
Description		hydroxysteroid 17-beta dehydrogenase 11	transmembrane protein 203
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity 17-beta-hydroxysteroid Dehydrogenase (NADP+) Activity	Protein Binding
	Biological Process	Estrogen Biosynthetic Process Androgen Catabolic Process	Cellular Calcium Ion Homeostasis Spermatogenesis
Pathways		Estrogen biosynthesis
Drugs		Aetiocholanolone
Diseases
GWAS		Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)
Interacting Genes		54 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VEZT YIPF6	39 interacting genes: ANK1 AQP6 ATP6AP2 CD3G CNR2 CPLX4 CREB3 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 HSD17B11 HSD17B13 KCNJ6 LMNA LY6G6C MANBAL MFSD5 MMD PDZK1IP1 RETREG3 RMDN3 RNASEK SLC10A6 SLC18A1 SSMEM1 STOM STX4 TIMMDC1 TMEM14B TMEM234 TMEM31 TMEM52B TMEM60 TMEM86B TMX2
Entrez ID		51170	94107
HPRD ID		10881	17496
Ensembl ID		ENSG00000198189	ENSG00000187713
Uniprot IDs		Q8NBQ5	Q969S6
PDB IDs		1YB1
Enriched GO Terms of Interacting Partners?
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