HSD17B11 and VEZT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		HSD17B11	VEZT
Description		hydroxysteroid 17-beta dehydrogenase 11	vezatin, adherens junctions transmembrane protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol	Acrosomal Vesicle Stereocilia Ankle Link Complex Nucleoplasm Cytosol Plasma Membrane Adherens Junction Integral Component Of Membrane Stereocilium Membrane
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity 17-beta-hydroxysteroid Dehydrogenase (NADP+) Activity	Myosin Binding
	Biological Process	Estrogen Biosynthetic Process Androgen Catabolic Process	Cell-cell Adhesion
Pathways		Estrogen biosynthesis
Drugs		Aetiocholanolone
Diseases
GWAS		Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)	Brain morphology (MOSTest) ( 32665545) Endometriosis ( 23104006 23472165 28537267) Pursuit maintenance gain ( 29064472)
Interacting Genes		54 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VEZT YIPF6	16 interacting genes: ANKS6 AQP6 C5 CMTM3 CREB3L1 GORAB HSD17B11 LRRC4C MTIF3 MYO7A PGRMC2 RMDN2 SACM1L TLCD4 TMEM201 TSNARE1
Entrez ID		51170	55591
HPRD ID		10881	11671
Ensembl ID		ENSG00000198189	ENSG00000028203
Uniprot IDs		Q8NBQ5	Q9HBM0
PDB IDs		1YB1
Enriched GO Terms of Interacting Partners?
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