PAX5 and CCL19

		PAX5	CCL19
Description		paired box 5	C-C motif chemokine ligand 19
Image
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle	Extracellular Region Extracellular Space
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Protein Binding Chemokine Activity CCR7 Chemokine Receptor Binding CCR10 Chemokine Receptor Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Humoral Immune Response Multicellular Organism Development Spermatogenesis Aging Animal Organ Morphogenesis Lateral Ventricle Development Cerebral Cortex Development Adult Behavior Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Cranial Skeleton Morphogenesis Anatomical Structure Development Negative Regulation Of Histone H3-K9 Methylation	Establishment Of T Cell Polarity Immunological Synapse Formation Dendritic Cell Chemotaxis Myeloid Dendritic Cell Chemotaxis Monocyte Chemotaxis Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Cellular Calcium Ion Homeostasis Inflammatory Response Immune Response Cell Communication G Protein-coupled Receptor Signaling Pathway Response To Virus Positive Regulation Of Glycoprotein Biosynthetic Process Neutrophil Chemotaxis T Cell Costimulation Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-12 Production Positive Regulation Of Tumor Necrosis Factor Production Response To Prostaglandin E Positive Regulation Of T Cell Proliferation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JUN Kinase Activity Positive Regulation Of GTPase Activity Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of T-helper 1 Cell Differentiation Positive Regulation Of Endocytosis Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Lymphocyte Chemotaxis Positive Regulation Of Receptor-mediated Endocytosis Cell Maturation Positive Regulation Of Chemotaxis Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Protein Kinase B Signaling Regulation Of Cell Projection Assembly Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Response To Nitric Oxide Positive Regulation Of Neutrophil Chemotaxis Mature Conventional Dendritic Cell Differentiation Cellular Response To Virus Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Cell Motility Positive Regulation Of Dendritic Cell Dendrite Assembly Negative Regulation Of Dendritic Cell Apoptotic Process
Pathways		RUNX1 regulates transcription of genes involved in BCR signaling	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alzheimer's disease ( 30636644) Bipolar disorder ( 33169155) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Coronary artery disease in type 1 diabetes ( 29695241) ghrelin levels ( 33852427) HIV-1 susceptibility ( 25786224) Intelligence ( 22449649) Major depressive disorder ( 27479909) Moderate to vigorous physical activity levels ( 29899525) Morning person ( 30696823) Obesity-related traits ( 22013104)	Metabolite levels ( 23823483) Rheumatoid arthritis ( 30423114 24390342)
Interacting Genes		55 interacting genes: ACOT12 BCAS2 C1orf109 CCL19 CCNC CDK3 CIB3 CKS1B CREBBP CSNK2A1 CXorf38 DAXX DTX2 EBF1 ETS1 FBLN1 GNG13 GRHL2 HGS HMBOX1 HMGB3 HOXC8 ID2 ID3 KLHL38 KPNA1 KPNA2 KRTAP10-8 KRTAP9-3 LARP4 LDLRAP1 LONRF1 MAPK1 MAPK9 MYB NEIL2 NFYC NGLY1 OSGIN1 PNMA5 RAD52 RB1 RNF144B RUNX1 SAE1 SEC14L4 STAC TBP TLE4 TLK2 UBE2I UBE3A UBXN2B UBXN7 ZMYM5	18 interacting genes: ACKR2 ACKR4 ATP6V0B B4GALT1 CCL22 CCR10 CCR7 CNTFR CXCL13 DCTN3 FZD7 GALT MEOX2 PAX5 PF4V1 PPM1E RPS4X TLN1
Entrez ID		5079	6363
HPRD ID		01334	03750
Ensembl ID		ENSG00000196092	ENSG00000172724
Uniprot IDs		C0KTE5 C0KTF5 E7EQT0 E7ERK2 E7ERW5 E7ES87 Q02548	Q6IBD6 Q99731
PDB IDs		1K78 1MDM	2MP1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?