PAX5 and UBXN7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PAX5	UBXN7
Description		paired box 5	UBX domain protein 7
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GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle	Nucleoplasm Cytosol Nuclear Body VCP-NPL4-UFD1 AAA ATPase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Protein Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Humoral Immune Response Multicellular Organism Development Spermatogenesis Aging Animal Organ Morphogenesis Lateral Ventricle Development Cerebral Cortex Development Adult Behavior Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Cranial Skeleton Morphogenesis Anatomical Structure Development Negative Regulation Of Histone H3-K9 Methylation
Pathways		RUNX1 regulates transcription of genes involved in BCR signaling	Neddylation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alzheimer's disease ( 30636644) Bipolar disorder ( 33169155) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Coronary artery disease in type 1 diabetes ( 29695241) ghrelin levels ( 33852427) HIV-1 susceptibility ( 25786224) Intelligence ( 22449649) Major depressive disorder ( 27479909) Moderate to vigorous physical activity levels ( 29899525) Morning person ( 30696823) Obesity-related traits ( 22013104)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) IgM levels ( 28628107)
Interacting Genes		55 interacting genes: ACOT12 BCAS2 C1orf109 CCL19 CCNC CDK3 CIB3 CKS1B CREBBP CSNK2A1 CXorf38 DAXX DTX2 EBF1 ETS1 FBLN1 GNG13 GRHL2 HGS HMBOX1 HMGB3 HOXC8 ID2 ID3 KLHL38 KPNA1 KPNA2 KRTAP10-8 KRTAP9-3 LARP4 LDLRAP1 LONRF1 MAPK1 MAPK9 MYB NEIL2 NFYC NGLY1 OSGIN1 PNMA5 RAD52 RB1 RNF144B RUNX1 SAE1 SEC14L4 STAC TBP TLE4 TLK2 UBE2I UBE3A UBXN2B UBXN7 ZMYM5	25 interacting genes: APP ATP13A3 CLEC19A CRX CYSRT1 DAZAP2 FAM168A MAP3K1 MEOX1 MUL1 NEDD8 NFYC PAX5 PAX6 REL SMURF1 TRAF6 TRIM39 TRIM62 TRIM8 UBC UBQLN1 UBQLN2 VCP ZNRF1
Entrez ID		5079	26043
HPRD ID		01334	19396
Ensembl ID		ENSG00000196092	ENSG00000163960
Uniprot IDs		C0KTE5 C0KTF5 E7EQT0 E7ERK2 E7ERW5 E7ES87 Q02548	O94888
PDB IDs		1K78 1MDM	1WJ4 2DAL 2DLX 5X3P 5X4L
Enriched GO Terms of Interacting Partners?
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