P4HB and ERO1A

Number of citations of the paper that reports this interaction (PubMedID 11707400)
93

Data Source:
HPRD (in vivo)

		P4HB	ERO1A
Description		prolyl 4-hydroxylase subunit beta	endoplasmic reticulum oxidoreductase 1 alpha
Image
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Cytoskeleton Focal Adhesion External Side Of Plasma Membrane Procollagen-proline 4-dioxygenase Complex Lamellipodium Protein-containing Complex Endoplasmic Reticulum Chaperone Complex Melanosome Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Disulfide Isomerase Activity Actin Binding Procollagen-proline 4-dioxygenase Activity Integrin Binding Protein Binding Protein-disulfide Reductase Activity Thiol Oxidase Activity Enzyme Binding Protein Heterodimerization Activity	Protein Disulfide Isomerase Activity Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Oxidoreductase Activity Thiol Oxidase Activity FAD Binding
	Biological Process	Protein Folding Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Interleukin-12-mediated Signaling Pathway Interleukin-23-mediated Signaling Pathway Positive Regulation Of Cell Adhesion Positive Regulation Of Viral Entry Into Host Cell Cellular Response To Hypoxia Cellular Response To Interleukin-7 Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Protein Folding Cellular Protein Modification Process Response To Oxidative Stress Response To Temperature Stimulus Animal Organ Senescence Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia
Pathways		Collagen biosynthesis and modifying enzymes Detoxification of Reactive Oxygen Species Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Hedgehog ligand biogenesis VLDL assembly Post-translational protein phosphorylation Chylomicron assembly Interleukin-12 signaling Interleukin-23 signaling	Insulin processing Detoxification of Reactive Oxygen Species
Drugs		Zinc Ribostamycin Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)
Interacting Genes		52 interacting genes: CD1D CHCHD2 CNNM3 COL10A1 COL1A1 COL1A2 CSNK2A2 CST2 EIF2S1 ENO1 ERN1 ERO1A ERO1B ESR1 FAM20C FAM71C FEZ1 FZD10 GRN HNRNPD ITGB3 KLHL42 KRTAP12-3 KRTAP13-2 KRTAP4-11 KRTAP5-9 KRTAP6-3 KRTAP9-8 LCE1B LCE2D LCE4A LCN2 LGALS9 LINC00839 LRFN4 NECTIN2 NOL4 NTM ODF1 OGT P4HA2 P4HA3 PLCXD3 PRNP PTN SUMO2 TG TGFB1 UBQLN1 VWF YWHAG ZNF69	15 interacting genes: APPBP2 DYNLT1 EBF1 ERP44 GPX7 GPX8 KLHDC2 LHX4 LINC01554 OGT P4HB PDIA3 PDILT PELI2 RHOU
Entrez ID		5034	30001
HPRD ID		07181	13278
Ensembl ID		ENSG00000185624	ENSG00000197930
Uniprot IDs		A0A024R8S5 P07237	Q96HE7
PDB IDs		1BJX 1MEK 1X5C 2BJX 2K18 3BJ5 3UEM 4EKZ 4EL1 4JU5 6I7S	3AHQ 3AHR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?