OXTR and MVB12A

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		OXTR	MVB12A
Description		oxytocin receptor	multivesicular body subunit 12A
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Microvillus Adherens Junction Apical Plasma Membrane	ESCRT I Complex Nucleoplasm Golgi Apparatus Centrosome Cytosol Endosome Membrane Late Endosome Membrane Vesicle Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Oxytocin Receptor Activity Vasopressin Receptor Activity Peptide Hormone Binding Peptide Binding	Protein Binding Lipid Binding SH3 Domain Binding Ubiquitin Binding
	Biological Process	Suckling Behavior Response To Amphetamine Regulation Of Systemic Arterial Blood Pressure By Vasopressin Muscle Contraction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Heart Development Female Pregnancy Lactation Memory Response To Xenobiotic Stimulus Positive Regulation Of Norepinephrine Secretion Telencephalon Development Sleep Positive Regulation Of Synaptic Transmission, GABAergic Response To Estradiol Response To Progesterone Response To Anoxia Response To Cytokine Social Behavior Response To Cocaine Maternal Behavior Sperm Ejaculation Eating Behavior Response To Peptide Hormone Estrous Cycle Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Digestive Tract Development Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Maternal Process Involved In Parturition Positive Regulation Of Penile Erection Negative Regulation Of Gastric Acid Secretion ERK1 And ERK2 Cascade Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Cold-induced Thermogenesis	Protein Transport Macroautophagy Virus Maturation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Receptor Catabolic Process Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding
Pathways		Vasopressin-like receptors G alpha (q) signalling events	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs		Oxytocin Carbetocin Atosiban Relcovaptan
Diseases
GWAS		Caudate activity during reward ( 28927378) Chronotype ( 30696823) Depression and alcohol dependence ( 22064162) Liver fibrosis severity in HIV/hepatitis C co-infection ( 27339598) Morning person ( 30696823)
Interacting Genes		18 interacting genes: ALAS1 ARRB2 ASH1L AVP CD81 CYFIP2 EMC10 FSCN1 GPRASP1 LCNL1 MVB12A OXT PSMA7 SIRT2 THOC5 TMEM161A TSPAN7 YIPF3	6 interacting genes: APP CD2AP HSF2BP OXTR PPP1R27 SH3KBP1
Entrez ID		5021	93343
HPRD ID		01328	14298
Ensembl ID		ENSG00000180914	ENSG00000141971
Uniprot IDs		B2R9L7 P30559	A0A024R7L6 Q96EY5
PDB IDs		6TPK	6VME
Enriched GO Terms of Interacting Partners?
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