SPANXN2 and SP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPANXN2	SP3
Description		SPANX family member N2	Sp3 transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm PML Body Transcription Repressor Complex Protein-DNA Complex
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Metal Ion Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Ossification Natural Killer Cell Differentiation Trophectodermal Cell Differentiation Liver Development Embryonic Placenta Development Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II B Cell Differentiation T Cell Differentiation Megakaryocyte Differentiation Monocyte Differentiation Lung Development Granulocyte Differentiation Enucleate Erythrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Camera-type Eye Morphogenesis Embryonic Skeletal System Development Embryonic Process Involved In Female Pregnancy Definitive Hemopoiesis
Pathways			SUMOylation of transcription factors
Drugs
Diseases
GWAS			End-stage renal disease in Type 1 diabetics ( 24029427) Lung cancer ( 28604730) Male-pattern baldness ( 27182965) Mosquito bite size ( 28199695) Otitis media (chronic/recurrent) ( 23974705) QT interval ( 24952745 29874175) Sensation seeking ( 30718321)
Interacting Genes		51 interacting genes: ANKRD1 ANKRD11 BANP BEND7 BHLHB9 BIVM CAVIN1 CDC14B CDCA8 CDYL2 COIL DPPA4 EPB41L3 FAM193B FAM204A H2BC11 H2BC15 H2BC21 KHDC4 KRCC1 L3MBTL3 MEOX2 MTIF3 NOL12 NUMB PBX4 PICK1 RPL27 RRP1 SFMBT1 SMN1 SMN2 SNIP1 SNRPD2 SP3 SP4 SRP14 STAC3 SYTL4 THAP1 TNNI1 VAX1 YAF2 ZBTB48 ZNF19 ZNF2 ZNF438 ZNF526 ZNF655 ZNF75A ZNF84	30 interacting genes: AKT1 CIB3 E2F1 EP300 ESR1 GABPA GCH1 GRIN1 HDAC1 HDAC2 HLTF LIN54 NKX3-1 PAK6 PHF21A PIAS1 POGZ RB1 RBBP4 RPS20 SNRPB SP1 SPANXN2 STK19 SUMO1 TP53 TP73 UBE2I VEGFA ZBTB7A
Entrez ID		494119	6670
HPRD ID		18091	03483
Ensembl ID		ENSG00000268988	ENSG00000172845
Uniprot IDs		Q5MJ10	B7ZLN9 Q02447 Q59FX5 Q86TP0
PDB IDs
Enriched GO Terms of Interacting Partners?
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