GPX8 and SGMS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPX8	SGMS2
Description		glutathione peroxidase 8 (putative)	sphingomyelin synthase 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Integral Component Of Membrane	Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Peroxidase Activity Glutathione Peroxidase Activity Protein Binding	Ceramide Phosphoethanolamine Synthase Activity Protein Binding Kinase Activity Sphingomyelin Synthase Activity Ceramide Cholinephosphotransferase Activity
	Biological Process	Cellular Response To Oxidative Stress Cellular Oxidant Detoxification	Sphingomyelin Biosynthetic Process Phosphorylation Sphingolipid Biosynthetic Process Regulation Of Bone Mineralization Ceramide Biosynthetic Process Ceramide Phosphoethanolamine Biosynthetic Process
Pathways		Detoxification of Reactive Oxygen Species	Sphingolipid de novo biosynthesis
Drugs		Glutathione Glutathione disulfide
Diseases
GWAS		Cocaine dependence ( 31212010)	Metabolite levels ( 23823483) Monoclonal gammopathy of undetermined significance ( 30737484) Obsessive-compulsive traits ( 33531474)
Interacting Genes		152 interacting genes: - AGTRAP AIG1 ALG8 APOC3 APOD AQP1 AQP2 AQP3 ASGR1 ASPH BCL2L2 BET1 BIK BMP10 BNIP2 BTN2A2 C14orf180 C1GALT1 CACNG1 CD302 CD53 CD81 CDIPT CDS2 CFHR5 CHST1 CLDN19 CLEC1A CLEC2A CMTM5 CNIH1 CNIH3 COL4A5 COL8A2 CORIN CYB561 CYB561A3 CYB561D2 DNAJC30 DOLK EDDM3B ERG28 ERO1A FA2H FAM3C FAXDC2 GET3 GOSR2 GPR151 GPR37L1 GRINA GYPA HHATL HMOX2 IGFBP5 INSIG2 KIR2DL3 KLRG1 LAPTM4B LEPROTL1 LHFPL5 LNPEP LPAR3 MAN2B2 MARCHF2 MARCHF5 MFSD5 MFSD6 MGST2 MGST3 MIP MMD MYADML2 NEU1 NINJ1 NIPAL3 NKG7 NRM OCLN PAEP PAQR5 PAQR6 PGAP2 PLLP PLN PLP2 PLPP4 PLPP6 PNLIPRP1 PRB1 RBFA RND1 RTP2 SCARB2 SCARF1 SCD SEC22B SELENOK SERINC1 SERINC2 SERP1 SERTM1 SFTPC SGMS2 SLC13A3 SLC30A3 SLC34A3 SLC35A1 SLC35B4 SLC41A2 SMAGP SNORC ST6GAL2 STX3 STX8 SYT15 TF THBD TIMMDC1 TM4SF4 TMBIM6 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14B TMEM19 TMEM218 TMEM229B TMEM243 TMEM254 TMEM42 TMEM50B TMEM60 TMEM86B TMEM97 TMPRSS4 TMUB2 TRAM1L1 TSPAN33 UNC50 UPK1B VAMP3 VAMP4 VAMP5 VKORC1L1 VSTM1 VTI1B YIF1A YIPF6 ZDHHC22	6 interacting genes: CTSA GPX8 LMNA LPAR3 VAMP1 ZFPL1
Entrez ID		493869	166929
HPRD ID		17416	11323
Ensembl ID		ENSG00000164294	ENSG00000164023
Uniprot IDs		B4DPY0 E7ETY7 J3KNB5 Q8TED1	A0A024RDH4 Q8NHU3
PDB IDs		3CYN 3KIJ
Enriched GO Terms of Interacting Partners?
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