MT2A and SPINK7

Number of citations of the paper that reports this interaction (PubMedID 12646258)
9

		MT2A	SPINK7
Description		metallothionein 2A	serine peptidase inhibitor Kazal type 7
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Extracellular Region
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Cellular Copper Ion Homeostasis Cellular Zinc Ion Homeostasis Detoxification Of Copper Ion Cellular Response To Interleukin-3 Cellular Response To Erythropoietin Negative Regulation Of Growth Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Zinc Ion	Negative Regulation Of Endopeptidase Activity
Pathways		Metallothioneins bind metals Metallothioneins bind metals Interferon gamma signaling
Drugs		Zinc Silver Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Experiencing mood swings ( 29500382)
Interacting Genes		20 interacting genes: ADAMTS4 ARF6 ASS1 BARD1 DHODH ECT2 EOLA1 HMGB1 JMJD1C LAMTOR5 MCPH1 PAXIP1 PRKD1 RCHY1 RIN3 SHBG SPINK7 STOM TNS2 USP25	9 interacting genes: EPB42 FTL GALNT10 HBA1 MRPS12 MT1G MT1H MT2A RABL6
Entrez ID		4502	84651
HPRD ID		08863	16850
Ensembl ID		ENSG00000125148	ENSG00000145879
Uniprot IDs		P02795	P58062
PDB IDs		1MHU 2MHU	2LEO
Enriched GO Terms of Interacting Partners?
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