MSX2 and POU2F2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MSX2	POU2F2
Description		msh homeobox 2	POU class 2 homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytosol Nuclear Speck	Chromatin Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Cardiac Conduction System Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Embryonic Morphogenesis Cranial Suture Morphogenesis Negative Regulation Of Transcription Regulatory Region DNA Binding	Regulation Of Transcription By RNA Polymerase II Humoral Immune Response Positive Regulation Of Interleukin-6 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus
Pathways		Regulation of RUNX2 expression and activity	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Alzheimer's disease ( 33074286) Blond vs. brown/black hair color ( 30531825) Chin dimples ( 27182965) Chronotype ( 30696823) Depressive symptoms (SSRI exposure interaction) ( 25649181) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Red vs. brown/black hair color ( 30531825) Resistant hypertension ( 30237584) Stroke ( 26089329)	Alcohol consumption (drinks per week) ( 30643258) Chronotype ( 30696823) Eosinophil counts ( 32888494) Meat-related diet ( 32066663) Monocyte count ( 32888494) Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016)
Interacting Genes		56 interacting genes: ATXN1 CCDC102B CEBPA CLIC3 DLX2 DLX5 EPHB6 FBXW2 FOXH1 GATA2 GTF2F1 GTF2F2 HOXC9 LENG8 MAGED1 MAPK1 MAPK1IP1L MAT2B MGAT5B MSX1 NAF1 NR3C1 PATZ1 PIAS2 PITX1 POLR3D POU1F1 POU2AF1 POU2F2 POU6F2 PPARG PRR13 RBPMS2 RHOXF2 ROR2 RUNX2 SMAP2 SOX5 SPEN TCF7L2 TENT5D TLE1 TLE2 TLE5 TLX3 TOLLIP TSSK3 USP54 VEZF1 XRCC5 XRCC6 YTHDF1 ZBTB17 ZC3H10 ZDHHC2 ZFHX3	15 interacting genes: AR ESR1 GAPDH HMGA1 HMGB2 MNAT1 MSX2 NR2F1 NR3C1 PGR POU2AF1 RXRA TBP TXNRD1 XRCC6
Entrez ID		4488	5452
HPRD ID		00421	01251
Ensembl ID		ENSG00000120149	ENSG00000028277
Uniprot IDs		P35548	B5ME60 H0YLL6 P09086
PDB IDs			1HDP
Enriched GO Terms of Interacting Partners?
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