MGST2 and CCL3L3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MGST2	CCL3L3
Description		microsomal glutathione S-transferase 2	C-C motif chemokine ligand 3 like 3
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Extracellular Space
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Identical Protein Binding Glutathione Binding	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Lipid Metabolic Process Glutathione Biosynthetic Process Response To Organonitrogen Compound Leukotriene Biosynthetic Process Response To Lipopolysaccharide Membrane Lipid Catabolic Process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Cellular Oxidant Detoxification	Monocyte Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		Glutathione conjugation Aflatoxin activation and detoxification	Chemokine receptors bind chemokines Interleukin-10 signaling
Drugs		Glutathione
Diseases
GWAS		Metabolite levels ( 23823483)	Body mass index ( 26426971)
Interacting Genes		23 interacting genes: ASIC1 BCL2L10 BCL2L2 C3orf52 CCL3L3 CLEC14A CREB3 CREB3L1 CTXN3 DNAJC30 GIMAP5 GJA8 GPX8 HDHD2 PLN PNKP SEC22A SEC22B SGCB STX8 TMEM167B TMEM207 VAMP3	6 interacting genes: ACKR2 CCR5 MGST2 SGTB SLC41A3 TMEM179B
Entrez ID		4258	414062
HPRD ID		03436	14426
Ensembl ID		ENSG00000085871	ENSG00000276085
Uniprot IDs		Q99735	P16619
PDB IDs		6SSR 6SSS 6SSU 6SSW
Enriched GO Terms of Interacting Partners?
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