MGST2 and ASIC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MGST2	ASIC1
Description		microsomal glutathione S-transferase 2	acid sensing ion channel subunit 1
Image
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Synapse
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Identical Protein Binding Glutathione Binding	Protein Binding Ligand-gated Sodium Channel Activity Ion Gated Channel Activity Acid-sensing Ion Channel Activity
	Biological Process	Lipid Metabolic Process Glutathione Biosynthetic Process Response To Organonitrogen Compound Leukotriene Biosynthetic Process Response To Lipopolysaccharide Membrane Lipid Catabolic Process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Cellular Oxidant Detoxification	Behavioral Fear Response Response To Amphetamine Sodium Ion Transport Signal Transduction Memory Associative Learning Response To PH Response To Acidic PH Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Negative Regulation Of Neurotransmitter Secretion Sensory Perception Of Sour Taste Protein Homotrimerization Calcium Ion Transmembrane Transport Cellular Response To PH
Pathways		Glutathione conjugation Aflatoxin activation and detoxification	Stimuli-sensing channels
Drugs		Glutathione	Amiloride
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		23 interacting genes: ASIC1 BCL2L10 BCL2L2 C3orf52 CCL3L3 CLEC14A CREB3 CREB3L1 CTXN3 DNAJC30 GIMAP5 GJA8 GPX8 HDHD2 PLN PNKP SEC22A SEC22B SGCB STX8 TMEM167B TMEM207 VAMP3	7 interacting genes: ASIC2 ATXN3 KIR3DL3 MGST2 PICK1 PRKACA STOM
Entrez ID		4258	41
HPRD ID		03436	04182
Ensembl ID		ENSG00000085871	ENSG00000110881
Uniprot IDs		Q99735	A8K1U5 P78348
PDB IDs		6SSR 6SSS 6SSU 6SSW	6L6I 6L6N 7CFS 7CFT
Enriched GO Terms of Interacting Partners?
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