MBD1 and NELL2

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		MBD1	NELL2
Description		methyl-CpG binding domain protein 1	neural EGFL like 2
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Extracellular Region Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding	Protein Kinase C Binding Calcium Ion Binding Protein Binding Heparin Binding
	Biological Process	Transcription By RNA Polymerase II Heart Development Aging Response To Xenobiotic Stimulus Negative Regulation Of Gene Expression Neuron Differentiation Response To Nutrient Levels Response To Estradiol Response To Cocaine Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Astrocyte Differentiation	Neuron Cellular Homeostasis
Pathways		SUMOylation of transcription cofactors	Regulation of commissural axon pathfinding by SLIT and ROBO
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464)	Inflammatory bowel disease ( 27569725) Waist circumference ( 28552196)
Interacting Genes		45 interacting genes: APP ATF7IP ATF7IP2 ATXN1L C1QBP CBX4 CBX5 CCDC136 CHAF1A COPE DVL3 ECT2 EEF1G GRN HDAC3 HIPK3 HTT JAG2 LTBP3 LTBP4 MDFI MEGF6 NELL1 NELL2 NOTCH1 NOTCH3 OASL PIAS1 PIAS2 POMGNT1 RNF2 SETDB1 SLC25A3 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SNAPC2 SP1 SUV39H1 TENM1 TNC ZNF384 ZNF512B	9 interacting genes: ARX ATN1 ATXN7 BRD4 CACNA1A GFI1B HOXA1 MBD1 PRKAR1A
Entrez ID		4152	4753
HPRD ID		01133	11891
Ensembl ID		ENSG00000141644	ENSG00000184613
Uniprot IDs		A8K654 B4DI41 B4DUR3 Q9UIS9	A0A024R0X1 B7Z625 Q99435
PDB IDs		1D9N 1IG4 4D4W 5W9Q 6D1T	6POG
Enriched GO Terms of Interacting Partners?
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