MBD1 and MEGF6

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		MBD1	MEGF6
Description		methyl-CpG binding domain protein 1	multiple EGF like domains 6
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Cellular_component Extracellular Region
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding	Calcium Ion Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase II Heart Development Aging Response To Xenobiotic Stimulus Negative Regulation Of Gene Expression Neuron Differentiation Response To Nutrient Levels Response To Estradiol Response To Cocaine Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Astrocyte Differentiation	Biological_process
Pathways		SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464)	Chronic central serous retinopathy ( 30073298) Systemic mastocytosis ( 32752121)
Interacting Genes		45 interacting genes: APP ATF7IP ATF7IP2 ATXN1L C1QBP CBX4 CBX5 CCDC136 CHAF1A COPE DVL3 ECT2 EEF1G GRN HDAC3 HIPK3 HTT JAG2 LTBP3 LTBP4 MDFI MEGF6 NELL1 NELL2 NOTCH1 NOTCH3 OASL PIAS1 PIAS2 POMGNT1 RNF2 SETDB1 SLC25A3 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SNAPC2 SP1 SUV39H1 TENM1 TNC ZNF384 ZNF512B	11 interacting genes: ATN1 ATXN7 CACNA1A CRKL EGFR GFI1B HOXA1 MBD1 MFAP5 NUFIP2 SHANK3
Entrez ID		4152	1953
HPRD ID		01133	11973
Ensembl ID		ENSG00000141644	ENSG00000162591
Uniprot IDs		A8K654 B4DI41 B4DUR3 Q9UIS9	O75095
PDB IDs		1D9N 1IG4 4D4W 5W9Q 6D1T
Enriched GO Terms of Interacting Partners?
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