NBR1 and GABARAPL2

Number of citations of the paper that reports this interaction (PubMedID 20562859)
678

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		NBR1	GABARAPL2
Description		NBR1 autophagy cargo receptor	GABA type A receptor associated protein like 2
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GO Annotations	Cellular Component	Phagophore Assembly Site Nucleoplasm Mitochondrion Mitochondrial Intermembrane Space Lysosome Late Endosome Autophagosome Peroxisomal Membrane Cytosol Membrane Nuclear Body M Band Intracellular Membrane-bounded Organelle Receptor Complex	Golgi Membrane Autophagosome Membrane Cytoplasm Autophagosome Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cytoplasmic Vesicle
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Binding Mitogen-activated Protein Kinase Binding	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding
	Biological Process	Macroautophagy Regulation Of Bone Mineralization Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Osteoblast Differentiation	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Protein Localization To Endoplasmic Reticulum Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways		Pexophagy Pexophagy	Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 34211149) Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)
Interacting Genes		21 interacting genes: ATXN1L AXIN1 CALM1 CIB1 FEZ1 GABARAP GABARAPL2 GSK3A GSK3B ITSN2 MAP1LC3A MAP2K4 METAP1 SQSTM1 SYT4 TTN UBC UBE2D2 UBE2D3 USP8 VTA1	91 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 BNIP3L BSDC1 CALCOCO1 CALCOCO2 CLN8 CUL3 DYNLL1 DYNLL2 EGFR ERBB2 ERBB3 ERBB4 FUNDC1 GIMAP6 GOSR1 GPM6A GPR37 HAP1 HSP90AB1 INSYN1 KASH5 KBTBD6 KBTBD7 KIAA1958 KIF16B KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 LZTR1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NPSR1 NSF NUDT15 OPTN OSBPL3 OSBPL7 PRKAR2A PTPRA RAP1A RAP2A RB1CC1 RCN2 RETREG1 RETREG3 RPS2 SCYL3 SGTA SIK2 SMO SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TEX264 TNIP1 TP53INP1 TP53INP2 TRIM21 TRIM32 TRIM45 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ ZBTB2 ZNF774
Entrez ID		4077	11345
HPRD ID		01326	16246
Ensembl ID		ENSG00000188554	ENSG00000034713
Uniprot IDs		A0A024R1V3 B7Z5R6 Q14596	P60520
PDB IDs		1WJ6 2BKF 2CP8 2G4S 2L8J 2MGW 2MJ5 4OLE	4CO7 6H8C
Enriched GO Terms of Interacting Partners?
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