GABARAPL2 and OSBPL7

Number of citations of the paper that reports this interaction (PubMedID 21669198)
2

Data Source:
BioGRID (two hybrid)

		GABARAPL2	OSBPL7
Description		GABA type A receptor associated protein like 2	oxysterol binding protein like 7
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Autophagosome Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cytoplasmic Vesicle	Nucleoplasm Autophagosome Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum
	Molecular Function	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Protein Localization To Endoplasmic Reticulum Negative Regulation Of Proteasomal Protein Catabolic Process	Bile Acid Biosynthetic Process Regulation Of Autophagy Sterol Transport Cellular Response To Cholesterol Positive Regulation Of Proteasomal Protein Catabolic Process
Pathways		Macroautophagy TBC/RABGAPs	Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)	Alzheimer's disease (cognitive decline) ( 23535033) Asthma ( 34103634 32296059 31619474) Asthma (childhood onset) ( 31036433) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 26426971) Cholesterol, total ( 24097068 25961943 20686565) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol ( 24097068 25961943 20686565) Pulse pressure ( 30224653) Type 2 diabetes ( 30054458) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		91 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 BNIP3L BSDC1 CALCOCO1 CALCOCO2 CLN8 CUL3 DYNLL1 DYNLL2 EGFR ERBB2 ERBB3 ERBB4 FUNDC1 GIMAP6 GOSR1 GPM6A GPR37 HAP1 HSP90AB1 INSYN1 KASH5 KBTBD6 KBTBD7 KIAA1958 KIF16B KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 LZTR1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NPSR1 NSF NUDT15 OPTN OSBPL3 OSBPL7 PRKAR2A PTPRA RAP1A RAP2A RB1CC1 RCN2 RETREG1 RETREG3 RPS2 SCYL3 SGTA SIK2 SMO SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TEX264 TNIP1 TP53INP1 TP53INP2 TRIM21 TRIM32 TRIM45 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ ZBTB2 ZNF774	2 interacting genes: GABARAPL2 IKZF3
Entrez ID		11345	114881
HPRD ID		16246	09477
Ensembl ID		ENSG00000034713	ENSG00000006025
Uniprot IDs		P60520	Q8WXP9 Q9BZF2
PDB IDs		4CO7 6H8C
Enriched GO Terms of Interacting Partners?
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