MIRLET7A3 and TRMT10C

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIRLET7A3	TRMT10C
Description		microRNA let-7a-3	tRNA methyltransferase 10C, mitochondrial RNase P subunit
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Mitochondrial Ribonuclease P Complex Mitochondrial Nucleoid
	Molecular Function		TRNA Binding RNA Binding Protein Binding TRNA (guanine-N1-)-methyltransferase Activity TRNA (adenine-N1-)-methyltransferase Activity Identical Protein Binding TRNA (guanine(9)-N(1))-methyltransferase Activity MRNA (adenine-N1-)-methyltransferase Activity
	Biological Process	Gene Silencing By MiRNA	Mitochondrial RNA 5'-end Processing TRNA Methylation Positive Regulation Of Mitochondrial Translation MRNA Methylation Mitochondrial TRNA Processing Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing
Pathways			tRNA processing in the mitochondrion tRNA modification in the mitochondrion rRNA processing in the mitochondrion
Drugs
Diseases
GWAS			Alcohol consumption (drinks per week) ( 30643258) Allergic disease (asthma, hay fever or eczema) ( 29083406) Diastolic blood pressure ( 30224653) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		100 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CPSF1 CPSF2 CSTF1 CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 TRMT10C U2SURP UPF1 UTP20 YBX1 YBX3 ZFR ZNF346	4 interacting genes: MIR15A MIRLET7A3 MT-TI OGT
Entrez ID		406883	54931
HPRD ID			15240
Ensembl ID		ENSG00000283990	ENSG00000174173
Uniprot IDs			Q7L0Y3
PDB IDs			5NFJ
Enriched GO Terms of Interacting Partners?
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