LDLRAD1 and UNC93B1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LDLRAD1	UNC93B1
Description		low density lipoprotein receptor class A domain containing 1	unc-93 homolog B1, TLR signaling regulator
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome
	Molecular Function	Protein Binding	Protein Binding Toll-like Receptor Binding
	Biological Process		Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus
Pathways			Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231)	Schizophrenia x sex interaction ( 34099189) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		34 interacting genes: ADGRG7 ANKRD46 AQP1 BNIP2 BNIP3 BNIP3L CMTM7 CTXN3 CXCL9 EBP EMP3 GIMAP5 GPR25 IGFBP5 LAPTM5 MAL MALL MARCHF2 NINJ2 OLFM4 PLN PLPP6 PTTG1IP SEC22A SLC1A1 SLC41A2 TMEM147 TMEM190 TMEM218 TMEM79 UNC93B1 VAMP4 VTI1B ZFPL1	27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237
Entrez ID		388633	81622
HPRD ID		17372	12191
Ensembl ID		ENSG00000203985	ENSG00000110057
Uniprot IDs		Q5T700	Q9H1C4
PDB IDs			7C76 7CYN
Enriched GO Terms of Interacting Partners?
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