TNFAIP8L3 and CBY1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TNFAIP8L3	CBY1
Description		TNF alpha induced protein 8 like 3	chibby family member 1, beta catenin antagonist
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane	Nucleus Nucleoplasm Trans-Golgi Network Centriole Cytosol Nuclear Speck Cell Projection
	Molecular Function	Protein Binding Phosphatidylinositol Transfer Activity Phosphatidylinositol Binding	Protein Binding Beta-catenin Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Phospholipid Metabolic Process Phospholipid Transport Regulation Of Lipid Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Inositol Lipid-mediated Signaling Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Intermembrane Lipid Transfer	Protein Localization Cell Projection Organization Negative Regulation Of Wnt Signaling Pathway Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Protein Homotetramerization Cardiac Muscle Cell Differentiation
Pathways		PI Metabolism	Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Airway wall thickness ( 25517131) Aspartate aminotransferase levels ( 33547301) Cognitive performance ( 20125193) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Keratoconus ( 33649486) Response to fenofibrate (HDL cholesterol levels) ( 27002377)	Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		2 interacting genes: CBY1 SDCBP	18 interacting genes: AGTPBP1 CDK6 CFAP53 CIBAR1 CLU CTNNB1 DDIAS DZIP1L ENKD1 FAM161B GORASP2 LNX1 NBPF11 RALBP1 RASSF10 TNFAIP8L3 TSG101 TTC23L
Entrez ID		388121	25776
HPRD ID		13452	09676
Ensembl ID		ENSG00000183578	ENSG00000100211
Uniprot IDs		A0A1B0GTK8 Q5GJ75	A0A024R1L9 A0A087WUW0 Q9Y3M2
PDB IDs		4Q9V	4WRQ
Enriched GO Terms of Interacting Partners?
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