CBY1 and RALBP1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		CBY1	RALBP1
Description		chibby family member 1, beta catenin antagonist	ralA binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Trans-Golgi Network Centriole Cytosol Nuclear Speck Cell Projection	Spindle Pole Nucleus Mitochondrion Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding Beta-catenin Binding Identical Protein Binding Protein Homodimerization Activity	GTPase Activator Activity Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process	Protein Localization Cell Projection Organization Negative Regulation Of Wnt Signaling Pathway Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Protein Homotetramerization Cardiac Muscle Cell Differentiation	Positive Regulation Of Protein Phosphorylation Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of Cdc42 Protein Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Positive Regulation Of Mitochondrial Fission Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		Deactivation of the beta-catenin transactivating complex	CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Resting heart rate ( 27798624) Sleep duration ( 30846698)	LDL cholesterol ( 30275531)
Interacting Genes		18 interacting genes: AGTPBP1 CDK6 CFAP53 CIBAR1 CLU CTNNB1 DDIAS DZIP1L ENKD1 FAM161B GORASP2 LNX1 NBPF11 RALBP1 RASSF10 TNFAIP8L3 TSG101 TTC23L	46 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF DLG4 FADD GAS8 GSE1 HOOK2 HSF1 IKBKG KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKACA PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TFPT TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707
Entrez ID		25776	10928
HPRD ID		09676	09013
Ensembl ID		ENSG00000100211	ENSG00000017797
Uniprot IDs		A0A024R1L9 A0A087WUW0 Q9Y3M2	Q15311
PDB IDs		4WRQ	2KWH 2KWI 2MBG 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?
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