KRT18 and KRT5

Number of citations of the paper that reports this interaction (PubMedID 9786957)
27

Data Source:
HPRD (in vivo)

		KRT18	KRT5
Description		keratin 18	keratin 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Microtubule Organizing Center Cytosol Intermediate Filament Adherens Junction External Side Of Plasma Membrane Protein-containing Complex Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome
	Molecular Function	RNA Binding Structural Molecule Activity Protein Binding Scaffold Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Cell Cycle Anatomical Structure Morphogenesis Response To Fructose Response To Nutrient Levels Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Hepatocyte Differentiation Mesenchymal Stem Cell Differentiation Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process Cell-cell Adhesion Cholangiocyte Apoptotic Process	Cytoskeleton Organization Epidermis Development
Pathways		Keratinization Formation of the cornified envelope	Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases
GWAS		Cleft lip with or without cleft palate ( 28054174) Diffusing capacity of carbon monoxide ( 30694715) Nonsyndromic cleft lip with cleft palate ( 28232668)	Basal cell carcinoma ( 31174203 33549134 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)
Interacting Genes		93 interacting genes: BBS1 BBS2 BBS4 BBS7 C1orf109 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCHCR1 CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EFHC1 EGFR EP300 ESR1 EXOC8 FRAT1 FXR1 FXR2 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 HSPB1 IKBKG KIFC3 KPNA2 KRT15 KRT5 KRT6A KRT6C KRT71 KRT72 KRT79 KRT8 KRT81 LDOC1 LINC01554 MAPK14 NEFL NME7 ORC5 PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE PSTPIP2 RAF1 RCOR3 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SVIL SYCE1 TCHP TEKT4 TNFRSF1B TRADD TSG101 TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A WBP2 YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ	35 interacting genes: ALOX12 ALOX12B APC DCTN1 DSP DST EVPL GPD1 INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT4 KRT40 KRT6A KRT6B KRT7 NADSYN1 PKP2 SAP18 SORD TARBP2 TCHP UBE3A
Entrez ID		3875	3852
HPRD ID		01020	01010
Ensembl ID		ENSG00000111057	ENSG00000186081
Uniprot IDs		A0A024RAY2 P05783	P13647
PDB IDs			3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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