KRT5 and KRT25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRT5	KRT25
Description		keratin 5	keratin 25
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	Molecular_function Structural Molecule Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Cytoskeleton Organization Epidermis Development	Cytoskeleton Organization Aging Hair Follicle Morphogenesis Hair Cycle Intermediate Filament Organization
Pathways		Type I hemidesmosome assembly Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases
GWAS		Basal cell carcinoma ( 31174203 33549134 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)	Asthma ( 31959851 30929738) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		35 interacting genes: ALOX12 ALOX12B APC DCTN1 DSP DST EVPL GPD1 INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT4 KRT40 KRT6A KRT6B KRT7 NADSYN1 PKP2 SAP18 SORD TARBP2 TCHP UBE3A	22 interacting genes: HGS KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT83 KRT85 KRT86 MORN4 PPL
Entrez ID		3852	147183
HPRD ID		01010	17242
Ensembl ID		ENSG00000186081	ENSG00000204897
Uniprot IDs		P13647	Q6ZPD6 Q7Z3Z0
PDB IDs		3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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