KRTAP10-3 and GLP1R

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		KRTAP10-3	GLP1R
Description		keratin associated protein 10-3	glucagon like peptide 1 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function		Transmembrane Signaling Receptor Activity Glucagon Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding Glucagon-like Peptide 1 Receptor Activity
	Biological Process		Cell Surface Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration CAMP-mediated Signaling Positive Regulation Of Blood Pressure Cellular Response To Glucagon Stimulus
Pathways		Keratinization	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs			Glucagon Exenatide Liraglutide Albiglutide Dulaglutide Lixisenatide Semaglutide
Diseases
GWAS			Blood sugar levels ( 29403010) Fasting blood glucose ( 25631608) Fasting blood glucose adjusted for BMI ( 25625282) Fasting glucose ( 34059833) Type 2 diabetes ( 32499647)
Interacting Genes		293 interacting genes: ACY3 ADAMTSL3 ADAMTSL4 ADAMTSL5 AEN ALDH3B1 ALPI ALPP AMMECR1 AP1M1 AQP1 AREG AVPI1 AXIN1 B4GALT7 BAHD1 BCL6B BMP7 BMS1P1 BRME1 BUD31 BYSL C10orf62 C22orf39 CARD9 CARHSP1 CATIP CATSPER1 CBX2 CCDC26 CCER1 CD164 CD300A CD300LG CDK5R1 CERK CHIC2 CHRD CHRNG CLDN2 CLK3 CLK4 COL8A1 CREB5 CST2 CST9L CTNNBIP1 CTRC CXCL16 DAAM2 DDX43 DDX6 DERL2 DHRS1 DHX57 DMRT3 DNAL4 DOCK2 EFNA3 EGFL8 ELOA FAM124B FAM161A FAM27E3 FAM71E2 FAM74A4 FAM76B FARS2 FBXL18 FBXW5 FOXB1 FZD9 GABARAPL1 GATA2 GEM GFOD1 GIP GLIDR GLIPR2 GLP1R GLRX3 GNE GNMT GOLGA8EP GPRIN2 GSTP1 GTF3C5 H2AW HBG1 HBZ HHEX HNRNPLL HOXA1 HPCAL1 HSBP1 HSD3B7 HSPD1 HYAL2 IGSF8 IL2RG INPP5D IQUB IWS1 JOSD1 KAT5 KCNK1 KIAA0040 KIF9 KLHL38 KLK15 KLK8 KRT83 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP13-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2A LCE3C LCE3E LIMS2 LINC00636 LINC01588 LMF2 LMNA LUZP4 LYVE1 MAPKBP1 MEOX2 MOBP MPP3 MRPL40 MXI1 NAA10 NAB2 NAXD NDUFAF3 NECTIN2 NECTIN3 NID2 NLK NOTCH2NLA NPBWR2 NPDC1 NPPB NUBP2 NUDCD3 NUFIP2 OLFM2 OPCML OTX1 P2RY6 PCED1A PCSK5 PDE9A PDIA5 PGAP2 PGAP6 PGLS PIGS PIN1 PKD2 PLSCR1 POLL PPARD PRKAA2 PRKAB2 PRKAG1 PRPF31 PTGDS PTGER3 PTPMT1 PTPRH PVR QPRT R3HDM2 RAB7A RAMP3 RHNO1 RNF175 RPS19BP1 RPS28 RPUSD3 RTN4RL1 SCNM1 SDC3 SDCBP SELENOM SERF2 SHFL SLC15A3 SLC23A1 SLC25A10 SLC25A48 SLC35A2 SLC43A2 SLC6A20 SMCO4 SMCP SMOC1 SNAI1 SNHG11 SPACA9 SPATA3 SPATA8 SPG7 SPINK2 SPRY1 SPRY2 STK16 TBC1D23 TEAD4 TEDC2 THAP10 THAP7 TINAGL1 TLE5 TMEM106C TNFRSF6B TNIP3 TNK2 TNP2 TNS2 TRIM42 TRPV6 TTC23 TXNDC5 TYMSOS TYRO3 UCP2 UNC45A UTP23 VPS11 WFDC10B WIF1 WT1 XCL1 YIPF3 ZBTB24 ZBTB9 ZFYVE21 ZFYVE26 ZMYND10 ZNF101 ZNF124 ZNF136 ZNF138 ZNF155 ZNF165 ZNF20 ZNF202 ZNF23 ZNF250 ZNF26 ZNF264 ZNF266 ZNF32 ZNF417 ZNF433 ZNF439 ZNF446 ZNF461 ZNF490 ZNF559 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF670 ZNF679 ZNF688 ZNF697 ZNF699 ZNF763 ZNF786 ZNF79 ZNF792 ZNRF2P1 ZSCAN21 ZSCAN26	113 interacting genes: ACSF3 AGXT AIG1 APH1A ARFRP1 ASGR2 ATP13A1 ATP5MC3 ATP6AP2 C18orf32 C4orf3 CALM1 CAND2 CAV1 CCDC167 CD63 CD81 CELA3B CEND1 CFI CLDN7 CLIP4 CLPS CNIH4 COMT CTLA4 CYSRT1 CYSTM1 DAD1 DHRS7 EBP ELOVL1 EMC7 EMP2 ERP29 FGL1 FTL GABBR2 GCG GJB1 GNAS GP2 GPR108 GPR37 GPRASP1 GRINA HAMP HPN IER3 IFITM3 KHK KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP17-1 KRTAP5-9 LAPTM4A LINC00269 MFSD5 MRPL22 MT-ATP6 MT-ND4L MTCH2 MYL6 NBPF19 NOTCH2NLA NRGN NUCKS1 OCIAD2 OST4 P4HTM PAM PAQR6 PGRMC1 PIGG POMT2 PPIB PRSS2 PSMD8 RAB5B RAB5C RNF5 RTN3 RTN4 RTRAF SAA1 SCGB2A1 SEC11C SELENOK SERPINA1 SLC15A4 SLC37A4 SPTSSA STMN1 STMN3 STOML2 SVOP SYNGR3 SYNGR4 SYS1 TM4SF4 TMBIM6 TMCO3 TMEM147 TMEM176B TOMM6 TSPAN13 UGT1A9 VAPB ZNF99
Entrez ID		386682	2740
HPRD ID		11189	00677
Ensembl ID		ENSG00000212935	ENSG00000112164
Uniprot IDs		P60369	A0A142FHB8 P43220
PDB IDs			3C59 3C5T 3IOL 4ZGM 5E94 5NX2 5OTT 5OTU 5OTV 5OTW 5OTX 5VEW 5VEX 6B3J 6GB1 6ORV 6VCB 6X18 6X19 6X1A 6XOX 7C2E 7LCI 7LCJ 7LCK
Enriched GO Terms of Interacting Partners?
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