GLP1R and STOML2

Number of citations of the paper that reports this interaction (PubMedID 23864651)
14

Data Source:
BioGRID (protein complementation assay, affinity chromatography technology)

		GLP1R	STOML2
Description		glucagon like peptide 1 receptor	stomatin like 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Immunological Synapse Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytoskeleton Actin Cytoskeleton Extrinsic Component Of Plasma Membrane Membrane Raft
	Molecular Function	Transmembrane Signaling Receptor Activity Glucagon Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding Glucagon-like Peptide 1 Receptor Activity	Signaling Receptor Binding Protein Binding GTPase Binding Cardiolipin Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration CAMP-mediated Signaling Positive Regulation Of Blood Pressure Cellular Response To Glucagon Stimulus	Mitochondrial Calcium Ion Transmembrane Transport Cellular Calcium Ion Homeostasis Mitochondrion Organization Lipid Localization Positive Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Interleukin-2 Production Mitochondrial Protein Processing CD4-positive, Alpha-beta T Cell Activation Mitochondrial ATP Synthesis Coupled Proton Transport T Cell Receptor Signaling Pathway Protein Complex Oligomerization Positive Regulation Of Mitochondrial DNA Replication Positive Regulation Of Cardiolipin Metabolic Process Stress-induced Mitochondrial Fusion
Pathways		Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production	Processing of SMDT1
Drugs		Glucagon Exenatide Liraglutide Albiglutide Dulaglutide Lixisenatide Semaglutide
Diseases
GWAS		Blood sugar levels ( 29403010) Fasting blood glucose ( 25631608) Fasting blood glucose adjusted for BMI ( 25625282) Fasting glucose ( 34059833) Type 2 diabetes ( 32499647)
Interacting Genes		113 interacting genes: ACSF3 AGXT AIG1 APH1A ARFRP1 ASGR2 ATP13A1 ATP5MC3 ATP6AP2 C18orf32 C4orf3 CALM1 CAND2 CAV1 CCDC167 CD63 CD81 CELA3B CEND1 CFI CLDN7 CLIP4 CLPS CNIH4 COMT CTLA4 CYSRT1 CYSTM1 DAD1 DHRS7 EBP ELOVL1 EMC7 EMP2 ERP29 FGL1 FTL GABBR2 GCG GJB1 GNAS GP2 GPR108 GPR37 GPRASP1 GRINA HAMP HPN IER3 IFITM3 KHK KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP17-1 KRTAP5-9 LAPTM4A LINC00269 MFSD5 MRPL22 MT-ATP6 MT-ND4L MTCH2 MYL6 NBPF19 NOTCH2NLA NRGN NUCKS1 OCIAD2 OST4 P4HTM PAM PAQR6 PGRMC1 PIGG POMT2 PPIB PRSS2 PSMD8 RAB5B RAB5C RNF5 RTN3 RTN4 RTRAF SAA1 SCGB2A1 SEC11C SELENOK SERPINA1 SLC15A4 SLC37A4 SPTSSA STMN1 STMN3 STOML2 SVOP SYNGR3 SYNGR4 SYS1 TM4SF4 TMBIM6 TMCO3 TMEM147 TMEM176B TOMM6 TSPAN13 UGT1A9 VAPB ZNF99	15 interacting genes: ACOT11 APP CDH1 GLP1R HSF4 LNX1 MCC OGT PEX7 RABAC1 RFXANK RNF38 RPS7 SUMO4 TAL1
Entrez ID		2740	30968
HPRD ID		00677	16310
Ensembl ID		ENSG00000112164	ENSG00000165283
Uniprot IDs		A0A142FHB8 P43220	A0A087WYB4 Q9UJZ1
PDB IDs		3C59 3C5T 3IOL 4ZGM 5E94 5NX2 5OTT 5OTU 5OTV 5OTW 5OTX 5VEW 5VEX 6B3J 6GB1 6ORV 6VCB 6X18 6X19 6X1A 6XOX 7C2E 7LCI 7LCJ 7LCK
Enriched GO Terms of Interacting Partners?
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