KCNN3 and ERMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCNN3	ERMP1
Description		potassium calcium-activated channel subfamily N member 3	endoplasmic reticulum metallopeptidase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity Calmodulin Binding Small Conductance Calcium-activated Potassium Channel Activity	Protein Binding Metalloexopeptidase Activity Metal Ion Binding
	Biological Process	Ion Transport Potassium Ion Transmembrane Transport	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress
Pathways		Ca2+ activated K+ channels
Drugs		Procaine Miconazole Trimebutine
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Atrial fibrillation ( 28416818 29290336 30061737 29892015 20173747 22544366) Bipolar disorder ( 31043756) Birth weight ( 31043758) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 28552196) Incident atrial fibrillation ( 28416818) Interleukin-6 levels ( 33517400) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Prevalent atrial fibrillation ( 28416818) Prostate cancer ( 23535732) Squamous cell lung carcinoma ( 28604730) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 28552196) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Asthma ( 31959851 31619474) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)
Interacting Genes		12 interacting genes: APP CALM1 CLCN7 CRABP2 EMD ERMP1 FCER1G HAX1 ILF2 NAPB SLC27A3 UBAP2L	38 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MLANA MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80
Entrez ID		3782	79956
HPRD ID		04283	17227
Ensembl ID		ENSG00000143603	ENSG00000099219
Uniprot IDs		A0A087WYJ0 Q9UGI6	Q6ZMD3 Q7Z2K6
PDB IDs
Enriched GO Terms of Interacting Partners?
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